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ZIRC
ZFIN ID: ZDB-FIG-140327-10
Lee et al., 2003 - The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons. Development (Cambridge, England)   130(12):2669-2679 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Pec-fin
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-25 to Pec-fin

Fig. 5 no soul/foxi1-expressing cells later disappear in the no soul mutant. Anterior is to the left. (A-B) 36 hpf embryos labeled with foxi1 showing that the anteriorly located foxi1-expressing cells are absent in the no soul mutant. (C-F) 36 hpf embryos labeled with ngn (C,D) and phox2a (E-F) showing their expression in the visceral sensory neurons are largely absent. (G,H) 36 hpf embryos labeled with phox2b showing that its expression in the VIIth and IXth ganglia is absent, while its expression in the Xth ganglia appear normal in the mutant. (I,J) 60 hpf embryos labeled with phox2a showing that the deficits continue in the no soul mutant. AV, anterior ventral lateral line; MHB, mid-hindbrain boundary; O, octaval/statoacoustic ganglion; OT, oculomotor and troclear motor nuclei; VII, geniculate ganglion; IX, petrosal ganglion; X, nodose ganglion. Scale bar: 100 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
foxi1 WT standard conditions Prim-25 epibranchial placode ISH
foxi1m809/m809 standard conditions Prim-25 epibranchial placode ISH
neurog1 WT standard conditions Prim-25 facial ganglion ISH
Prim-25 glossopharyngeal ganglion ISH
Prim-25 statoacoustic (VIII) ganglion ISH
Prim-25 vagal ganglion ISH
Prim-25 ventral anterior lateral line ganglion ISH
foxi1m809/m809 standard conditions Prim-25 vagal ganglion ISH
phox2a WT standard conditions Prim-25 facial ganglion ISH
Prim-25 glossopharyngeal ganglion ISH
Prim-25 trochlear motor nucleus ISH
Prim-25 vagal ganglion ISH
Pec-fin trochlear motor nucleus ISH
Pec-fin vagal ganglion ISH
foxi1m809/m809 standard conditions Prim-25 facial ganglion ISH
Prim-25 glossopharyngeal ganglion ISH
Prim-25 trochlear motor nucleus ISH
Prim-25 vagal ganglion ISH
Pec-fin trochlear motor nucleus ISH
Pec-fin vagal ganglion ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
foxi1m809/m809 standard conditions Prim-25 facial ganglion absent, abnormal
Prim-25 glossopharyngeal ganglion absent, abnormal
Prim-25 vagal ganglion decreased size, abnormal
Prim-25 vagal ganglion lacks parts or has fewer parts of type vagal ganglion, abnormal
Prim-25 ventral anterior lateral line ganglion absent, abnormal
Pec-fin facial ganglion absent, abnormal
Pec-fin glossopharyngeal ganglion absent, abnormal
Pec-fin vagal ganglion decreased size, abnormal
Pec-fin vagal ganglion lacks parts or has fewer parts of type vagal ganglion, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development