Gene

foxi1

ID
ZDB-GENE-030505-1
Name
forkhead box i1
Symbol
foxi1 Nomenclature History
Previous Names
  • nos
  • cb724 (1)
  • hearsay
  • hsy
  • no soul
  • quadro (1)
  • quo(l)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including animal organ development; epidermal cell fate specification; and neuron development. Predicted to be located in nucleus. Is expressed in several structures, including ectoderm; epibranchial ganglion; head; neural crest; and neurogenic field. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Orthologous to human FOXI1 (forkhead box I1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
69 figures from 45 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
38 figures from 19 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxi1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 4 Alliance Enlarged vestibular aqueduct 600791
Associated With foxi1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q804B2 377
UniProtKB:Q7T2N8 419
UniProtKB:Q6DG75 377
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations