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ZFIN ID: ZDB-FIG-140219-20
Williams et al., 2013 - Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio. PLoS One   8(10):e79574 Full text @ PLoS One
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 6

Otic Vesicle Defects in nfe2 morphants.

Otic vesicles were laterally imaged at 30 hpf (panel A, D), 48 hpf (panel B, E), and 72 hpf (panel C, F) following injection of control MO (panels A, B, C) or nfe2-MO-1 (panels D, E, F) at the one to four-cell stage. Otoliths are marked with an arrowhead and projections of epithelium forming the semicircular canal system are noted with an arrow in panel B. The fusion of the canal system is noted by an arrow in panel C. Scale bars equal 50 μm.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nfe2 standard conditions Long-pec lapillus position, normal
Long-pec otic vesicle morphology, normal
Long-pec sagitta position, normal
Protruding-mouth lapillus mislocalised, abnormal
Protruding-mouth otic vesicle protrusion absent, abnormal
Protruding-mouth sagitta mislocalised, abnormal
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One