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General Information
ZIRC
ZFIN ID: ZDB-FIG-121025-48
Ben Shoham et al., 2012 - S1P1 inhibits sprouting angiogenesis during vascular development. Development (Cambridge, England)   139(20):3859-3869 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 9

Both Vegfa-dependent and -independent effects of S1p1 on vascular development in zebrafish. Fluorescence microscopy of 48 hpf control and s1p1 MO zebrafish embryos. Left panel: SIV of untreated (control), DMSO-treated and 5 μM SU5416-treated embryos; right panel: CVP of untreated (control), DMSO-treated and 5 μM-SU5416 treated embryos.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg chemical treatment: semaxanib Long-pec caudal vein plexus morphology, normal
Long-pec subintestinal vein morphology, abnormal
y1Tg + MO2-s1pr1 chemical treatment: semaxanib Long-pec caudal vein plexus morphology, abnormal
Long-pec subintestinal vein morphology, abnormal
y1Tg + MO2-s1pr1 standard conditions Long-pec caudal vein plexus morphology, abnormal
Long-pec subintestinal vein morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development