FIGURE

Fig. 3

ID
ZDB-FIG-120815-54
Publication
Tsai et al., 2012 - The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos
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Fig. 3

Growth hormone (GH)-treated tbx5 -knockdown zebrafish embryos show reduced apoptosis at 30 h post-fertilization (hpf). A TUNEL assay revealed no apoptotic spots in WT (A), MIS (B), and WTGH (C) embryos. (D) However, massive apoptotic spots were visible in MO embryos. (E) In the MOGH group, apoptotic sites were reduced. (A-E) Embryo anteriors are to the left. Scale bar = 0.1 cm. Black arrow, apoptotic site; WT, wild-type embryos; MO, tbx5 knockdown; MIS, mismatched tbx5-MO-treated embryos; WTGH, WT embryos treated with GH; MOGH, tbx5-MO- and GH-treated embryos.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage: Prim-15

Phenotype Detail
Acknowledgments
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