FIGURE

Fig. 4

ID

ZDB-FIG-120227-5

Publication

Odenthal et al., 1996 - Mutations affecting the formation of the notochord in the zebrafish, Danio rerio

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Fig. 4

Dorsal view (anterior to the left) of the expression pattern of the floor plate marker shh at the 15-somite stage in (A) wild-type, (B) flh^tk241, (C) mom^th211, (D) nt^ltc41, (E) ntl^ts260 and (F) doc^tt258 embryos. (A) At the 15-somite stage shh is expressed in the notochord (weak, out of focus) and in the midline floor plate cell of the spinal cord (strong). (C) In mom^th211 embryos shh is expressed in a few faintly labeled cells in the ventral spinal cord. These cells frequently overlie cells in the dorsal mesoderm expressing both shh and ntl (arrowheads, out of focus). (D) Note that in embryos with the strong allele, ntl^tc41, no expression of shh in the axial mesoderm is detectable. (E) Axial mesodermal expression of shh is strongly reduced in mutant embryos with the weak allele, ntl^ts260.

Expression Data

Gene:	shha
Fish:	WT dharma^th211/th211 doc^tt258/tt258 noto^tk241/tk241 tbxta^tc41/tc41 tbxta^ts260/ts260
Anatomical Terms:	axial mesoderm floor plate neural tube notochord spinal cord neural tube ventral region
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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