ZFIN ID: ZDB-FIG-091117-20
Odenthal et al., 1996 - Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development (Cambridge, England)   123:103-115 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: 10-13 somites to Pec-fin

Fig. 1

Images of live mutant embryos. Anterior is left, dorsal is top in all pictures, except in G-I, which are dorsal views. (A) 24-hour old wild-type embryo. (B) flhtk241 embryo; a small patch of floor plate in the ventral neural tube is indicated by an arrowhead. (C) momth211 embryo. (D) ntl embryo with the strongest allele, ntltc41. (E) ntlts260, the weak allele produces a reduced ventral tailfin. (F) doctt258 embryo. (G-I) Dorsal view of 10-somite stage embryos: (G) wild type, (H) momth211 and (I) doctt258. (J-K) Heads of 48-hour (J) wild-type and (K) mom larvae in a lateral view. (L) Tailtip of a 60 hour doctt258 larva.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dharmath211/th211 standard conditions 10-13 somites trunk has fewer parts of type notochord cell, abnormal
Prim-5 floor plate decreased size, abnormal
Prim-5 floor plate formation disrupted, abnormal
Prim-5 notochord formation disrupted, abnormal
Prim-5 notochord posterior region present, normal
Prim-5 somite fused with somite, abnormal
Prim-5 trunk notochord aplastic, abnormal
Long-pec eye decreased size, abnormal
Long-pec head morphology, abnormal
doctt258/tt258 standard conditions 10-13 somites notochord decreased thickness, abnormal
Prim-5 axial mesoderm undifferentiated, abnormal
Pec-fin notochord cell structure, cavities, abnormal
Pec-fin notochord formation disrupted, abnormal
nototk241/tk241 standard conditions Prim-5 floor plate decreased size, abnormal
Prim-5 floor plate formation disrupted, abnormal
Prim-5 notochord absent, abnormal
Prim-5 notochord formation disrupted, abnormal
Prim-5 somite fused with somite, abnormal
tbxtatc41/tc41 standard conditions Prim-5 notochord formation disrupted, abnormal
Prim-5 notochord posterior region absent, abnormal
Prim-5 post-anal tail morphogenesis disrupted, abnormal
Prim-5 post-vent region aplastic, abnormal
Prim-5 somite fused with somite, abnormal
tbxtats260/ts260 standard conditions Prim-5 post-anal tail morphogenesis disrupted, abnormal
Prim-5 post-vent region decreased length, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development