ZFIN ID: ZDB-FIG-100226-68
Stewart et al., 2009 - A histone demethylase is necessary for regeneration in zebrafish. Proceedings of the National Academy of Sciences of the United States of America   106(47):19889-19894 Full text @ Proc. Natl. Acad. Sci. USA
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Day 4

Fig. 4

Kdm6b.1 is needed for fin regeneration. Analysis of regeneration in control versus Kdm6b.1 MO1, MO3, or MO4 injected animals was followed over time in individual animals. Representative examples of a control (upper panels) and Kdm6b.1 MO (lower panels) phenotypes are shown before amputation, immediately after amputation, and 24 and 48 h after amputation. The amputation planes are similar to that shown above and the same animal is shown before and after amputation up to 48 h.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-kdm6bb physical alteration: anatomical structure Day 4 caudal fin blastema decreased size, abnormal
Day 4 fin regeneration disrupted, abnormal
WT + MO2-kdm6bb physical alteration: anatomical structure Day 4 caudal fin blastema decreased size, abnormal
Day 4 fin regeneration disrupted, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Proceedings of the National Academy of Sciences of the United States of America for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Proc. Natl. Acad. Sci. USA