ZFIN ID: ZDB-FIG-100226-67
Tse et al., 2009 - Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics   10:637 Full text @ BMC Genomics
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 4

Fig. S4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-alg13 standard conditions Prim-5 trunk immature, abnormal
Protruding-mouth central nervous system necrotic, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth trunk decreased thickness, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-atxn3 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth axis specification disrupted, abnormal
Protruding-mouth post-vent region malformed, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-bap1 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Prim-5 trunk necrotic, abnormal
Day 4 head hemorrhagic, abnormal
Day 4 notochord malformed, abnormal
Day 4 post-vent region curled, abnormal
AB + MO1-cops6 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Day 4 axis specification disrupted, abnormal
Day 4 extension aplastic, abnormal
Day 4 eye decreased size, abnormal
Day 4 head decreased size, abnormal
Day 4 notochord decreased length, abnormal
Day 4 pericardium edematous, abnormal
Day 4 whole organism decreased size, abnormal
AB + MO1-cylda standard conditions Prim-5 central nervous system necrotic, abnormal
Long-pec head malformed, abnormal
Long-pec midbrain increased size, abnormal
Long-pec midbrain hindbrain boundary decreased thickness, abnormal
Long-pec post-vent region curled, abnormal
AB + MO1-cyldb standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 trunk necrotic, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec pericardium edematous, abnormal
Long-pec trunk bent, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-eif3f standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth otolith morphogenesis disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-eif3ha standard conditions Protruding-mouth extension aplastic, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth post-vent region necrotic, abnormal
Protruding-mouth trunk bent, abnormal
AB + MO1-eif3hb standard conditions Prim-5 head immature, abnormal
Prim-5 somite immature, abnormal
Day 4 extension decreased length, abnormal
Day 4 pigmentation decreased occurrence, abnormal
Day 4 trunk bent, abnormal
AB + MO1-josd1 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Prim-5 trunk necrotic, abnormal
Protruding-mouth eye malformed, abnormal
Protruding-mouth floor plate deformed, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth post-vent region hemorrhagic, abnormal
Protruding-mouth somite fused with somite, abnormal
Protruding-mouth yolk deformed, abnormal
AB + MO1-josd2 standard conditions Prim-5 head malformed, abnormal
Prim-5 somite fused with somite, abnormal
Day 4 axis specification disrupted, abnormal
Day 4 head malformed, abnormal
Day 4 notochord malformed, abnormal
Day 4 optic tectum increased size, abnormal
Day 4 pericardium edematous, abnormal
Day 4 post-vent region curled, abnormal
Day 4 whole organism decreased size, abnormal
AB + MO1-mpnd standard conditions Day 4 extension aplastic, abnormal
Day 4 eye decreased size, abnormal
Day 4 head decreased size, abnormal
Day 4 pigmentation decreased occurrence, abnormal
Day 4 yolk deformed, abnormal
AB + MO1-mysm1 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region curled, abnormal
Protruding-mouth extension decreased length, abnormal
Protruding-mouth eye malformed, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth otolith morphogenesis disrupted, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth yolk deformed, abnormal
AB + MO1-otub1a standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec extension decreased thickness, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-otud3 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Prim-5 trunk necrotic, abnormal
Protruding-mouth axis specification disrupted, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth post-vent region curled, abnormal
AB + MO1-otud4 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Day 4 axis specification disrupted, abnormal
Day 4 head malformed, abnormal
Day 4 post-vent region curled, abnormal
Day 4 trunk decreased thickness, abnormal
Day 4 whole organism decreased size, abnormal
AB + MO1-otud5a standard conditions Protruding-mouth axis specification disrupted, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-otud5b standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth extension decreased thickness, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth trunk bent, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-psmd7 standard conditions Prim-5 central nervous system necrotic, abnormal
Long-pec extension decreased length, abnormal
Long-pec head immature, abnormal
Long-pec notochord decreased length, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region malformed, abnormal
Long-pec somite fused with somite, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-tnfaip3 standard conditions Prim-5 post-vent region necrotic, abnormal
Prim-5 trunk necrotic, abnormal
Day 4 head malformed, abnormal
Day 4 notochord development disrupted, abnormal
Day 4 pericardium edematous, abnormal
Day 4 post-vent region curled, abnormal
Day 4 trunk decreased thickness, abnormal
AB + MO1-uchl3 standard conditions Prim-5 somite fused with somite, abnormal
Prim-5 trunk necrotic, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-uchl5 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 head malformed, abnormal
Prim-5 somite fused with somite, abnormal
Day 4 extension decreased thickness, abnormal
Day 4 mandibular arch skeleton increased thickness, abnormal
Day 4 otolith morphogenesis disrupted, abnormal
Day 4 pericardium edematous, abnormal
Day 4 post-vent region curled, abnormal
AB + MO1-usp1 standard conditions Long-pec notochord development disrupted, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk bent, abnormal
Long-pec trunk decreased thickness, abnormal
AB + MO1-usp10 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec caudal fin deformed, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism curved ventral, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp11 standard conditions Long-pec extension decreased thickness, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk bent, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp12b standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region necrotic, abnormal
Day 4 extension decreased thickness, abnormal
Day 4 notochord development disrupted, abnormal
Day 4 pericardium edematous, abnormal
Day 4 post-vent region curled, abnormal
Day 4 yolk deformed, abnormal
AB + MO1-usp13 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec pericardium edematous, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp15 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region curled, abnormal
Long-pec somite fused with somite, abnormal
Day 4 eye malformed, abnormal
Day 4 gut immature, abnormal
Day 4 head malformed, abnormal
Day 4 liver immature, abnormal
Day 4 post-vent region necrotic, abnormal
Day 4 trunk edematous, abnormal
AB + MO1-usp16l standard conditions Prim-5 head necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec axis specification disrupted, abnormal
Long-pec eye immature, abnormal
Long-pec notochord decreased length, abnormal
Long-pec post-vent region curled, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp22 standard conditions Long-pec brain bulbous, abnormal
AB + MO1-usp28 standard conditions Prim-5 head damaged, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec central nervous system necrotic, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk decreased thickness, abnormal
AB + MO1-usp2b standard conditions Long-pec extension decreased thickness, abnormal
Long-pec trunk bent, abnormal
Long-pec trunk decreased thickness, abnormal
AB + MO1-usp36 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 trunk immature, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth trunk decreased thickness, abnormal
Protruding-mouth whole organism decreased size, abnormal
Protruding-mouth yolk deformed, abnormal
AB + MO1-usp39 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region necrotic, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region curled, abnormal
Long-pec somite fused with somite, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp4 standard conditions Prim-5 central nervous system necrotic, abnormal
Long-pec extension decreased thickness, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec post-vent region curled, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp42 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth hindbrain bulbous, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth trunk bent, abnormal
AB + MO1-usp43a standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec eye decreased size, abnormal
Long-pec forebrain bulbous, abnormal
Long-pec head decreased size, abnormal
Long-pec pericardium edematous, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region curled, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp44 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 embryo development disrupted, abnormal
Prim-5 post-vent region necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth head immature, abnormal
Protruding-mouth notochord decreased length, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth trunk immature, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-usp45 standard conditions Prim-5 central nervous system necrotic, abnormal
Long-pec extension decreased thickness, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec otolith morphogenesis disrupted, abnormal
Long-pec pericardium edematous, abnormal
Long-pec pigmentation decreased occurrence, abnormal
AB + MO1-usp48 standard conditions Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth post-vent region necrotic, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-usp5 standard conditions Prim-5 caudal fin upper lobe fused with caudal fin lower lobe, abnormal
Prim-5 central nervous system necrotic, abnormal
Prim-5 trunk immature, abnormal
Long-pec eye decreased size, abnormal
Long-pec head malformed, abnormal
Long-pec notochord decreased length, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region curled, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO1-usp7 standard conditions Prim-5 central nervous system necrotic, abnormal
Long-pec caudal fin deformed, abnormal
Long-pec caudal fin upper lobe fused with caudal fin lower lobe, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec whole organism decreased size, abnormal
Protruding-mouth otolith morphogenesis disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
AB + MO1-usp8 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Prim-5 trunk necrotic, abnormal
Protruding-mouth central nervous system necrotic, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth somite fused with somite, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-vcpip1 standard conditions Prim-5 caudal fin upper lobe fused with caudal fin lower lobe, abnormal
Prim-5 notochord immature, abnormal
Prim-5 notochord development disrupted, abnormal
Prim-5 trunk immature, abnormal
Day 4 eye decreased size, abnormal
Day 4 head decreased size, abnormal
Day 4 post-vent region curled, abnormal
Day 4 somite malformed, abnormal
Day 4 trunk decreased thickness, abnormal
Day 4 whole organism decreased size, abnormal
AB + MO1-yod1 standard conditions Protruding-mouth axis specification disrupted, abnormal
Protruding-mouth gut immature, abnormal
Protruding-mouth liver immature, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth somite fused with somite, abnormal
Protruding-mouth trunk edematous, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO1-zranb1b standard conditions Prim-5 post-vent region curled, abnormal
Prim-5 somite fused with somite, abnormal
Protruding-mouth extension aplastic, abnormal
Protruding-mouth notochord malformed, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
AB + MO2-usp3 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec caudal fin upper lobe fused with caudal fin lower lobe, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec optic tectum increased size, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region curled, abnormal
Long-pec trunk bent, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism decreased size, abnormal
AB + MO2-usp53a standard conditions Protruding-mouth brain bulbous, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth pigmentation decreased occurrence, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
WT + MO1-usp18 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec post-vent region necrotic, abnormal
Long-pec trunk immature, abnormal
Day 4 eye decreased size, abnormal
Day 4 head decreased size, abnormal
Day 4 notochord decreased length, abnormal
Day 4 pericardium edematous, abnormal
Day 4 post-vent region curled, abnormal
Day 4 trunk decreased thickness, abnormal
Day 4 whole organism decreased size, abnormal
Day 4 yolk deformed, abnormal
WT + MO1-usp19 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec notochord decreased length, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region curled, abnormal
Long-pec whole organism decreased size, abnormal
WT + MO1-usp20 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 somite fused with somite, abnormal
Long-pec head decreased size, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec post-vent region necrotic, abnormal
Long-pec whole organism decreased size, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region curled, abnormal
WT + MO1-usp21 standard conditions Prim-5 whole organism necrotic, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth head immature, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
WT + MO1-usp24 standard conditions Prim-5 somite fused with somite, abnormal
Prim-5 whole organism necrotic, abnormal
Long-pec central nervous system necrotic, abnormal
Long-pec eye malformed, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec post-vent region curled, abnormal
Long-pec post-vent region necrotic, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec whole organism decreased size, abnormal
WT + MO1-usp25 standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 post-vent region necrotic, abnormal
Long-pec central nervous system necrotic, abnormal
Long-pec forebrain bulbous, abnormal
Long-pec head malformed, abnormal
Long-pec post-vent region necrotic, abnormal
Long-pec somite fused with somite, abnormal
Long-pec trunk decreased thickness, abnormal
Long-pec trunk immature, abnormal
Long-pec whole organism decreased size, abnormal
WT + MO1-usp33 standard conditions Prim-5 central nervous system necrotic, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth post-vent region curled, abnormal
Protruding-mouth whole organism decreased size, abnormal
Acknowledgments:
ZFIN wishes to thank the journal BMC Genomics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ BMC Genomics