ZFIN ID: ZDB-FIG-091113-117
Sanek et al., 2009 - Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression. Development (Cambridge, England)   136(22):3791-3800 Full text @ Development
Anatomical Term:
Stage: 14-19 somites

Fig. 8 Hh is necessary and sufficient for zic2a expression in the OS and ventral retina. (A-F) zic2a is expressed in the OS at 16s (A). In smo-/- mutants, zic2a expression is reduced in the OS at this stage (B, 14/14 embryos, n=2), but not elsewhere. shha mRNA-injected WT embryos express zic2a ectopically in the OS and retina at 16s (C, 13/13 embryos, n=1). zic2a expression is still reduced in smo-/- mutants at 19s (D,E, 30/30 embryos, n=2), and expanded in shha-injected retina (F, 19/19 embryos, n=1). The same result was observed at prim-5 (39/42 embryos, n=2, data not shown). Arrowheads point to the OS. Embryos are in lateral view, anterior to the left.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
zic2a AB standard conditions 14-19 somites optic stalk ISH
smob641/b641 standard conditions 14-19 somites optic stalk ISH
Antibody Labeling Details No data available
Phenotype Details No data available
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