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ZIRC
ZFIN ID: ZDB-FIG-090622-14
Miller et al., 2003 - Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint. Development (Cambridge, England)   130(7):1353-1365 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. 3 edn1 function is required for jaw joint bapx1 expression. (A-D) bapx1 expression in wild-type (A,C) and edn1 mutant larvae (B,D). (A,B) Lateral views of 36 hpf embryos, focused on the first arch joint domain (arrow in A). First arch mesenchymal expression of bapx1 is absent in edn1 mutants (B). Cells apposed to the eye and the first pharyngeal pouch express bapx1 in both wild types and mutants. (C,D) Ventral views of 54 hpf embryos. Joint domains (arrows in C,D) are abolished in edn1 mutants, whereas the first and second arch midline domains (white and black arrowheads, respectively, in C and D) are present. Inset (D) shows lateral view of same embryo, showing both midline domains are present. Scale bars: 50 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
nkx3-2 WT standard conditions Prim-25 head ISH
Prim-25 pharyngeal arch 1 joint ISH
Prim-25 pharyngeal arch 1 mesenchyme ISH
Long-pec pharyngeal arch 1 ISH
Long-pec pharyngeal arch 1 joint ISH
Long-pec pharyngeal arch 2 ISH
edn1tf216b/tf216b standard conditions Prim-25 head ISH
Prim-25 Not Detected pharyngeal arch 1 joint ISH
Prim-25 Not Detected pharyngeal arch 1 mesenchyme ISH
Long-pec pharyngeal arch 1 ISH
Long-pec Not Detected pharyngeal arch 1 joint ISH
Long-pec pharyngeal arch 2 ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
edn1tf216b/tf216b standard conditions Prim-25 embryonic viscerocranium morphogenesis disrupted, abnormal
Prim-25 pharyngeal arch 1 joint physical object quality, abnormal
Long-pec embryonic viscerocranium morphogenesis disrupted, abnormal
Long-pec pharyngeal arch 1 joint physical object quality, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development