ZFIN ID: ZDB-FIG-070802-25
Plaster et al., 2007 - REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists   236(7):1891-1904 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 7 rerea and fgf8 interact during formation of the endodermal pouches. A-D: All panels show dorsal views, with anterior to the left, of whole-mount in situ hybridizations of wild-type (A,C) and bab;ace (B,D) embryos. Probes are shown in the lower left corner, whereas stages are in the lower right. Combined disruption of rerea and fgf8 leads to loss of the posterior endodermal pouches as seen by nkx2.3 expression (A,B) while medial endoderm (foxa2) remains (C,D). Horizontal bars (C,D) mark the anterior-posterior extent of the pharyngeal endoderm. p1-5, endodermal pouches 1-5; pe, posterior endoderm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
foxa2 WT standard conditions Long-pec endoderm ISH
fgf8ati282a/ti282a; rereatb210/tb210 standard conditions Long-pec endoderm ISH
nkx2.3 WT standard conditions Long-pec endoderm ISH
Long-pec pharyngeal pouch ISH
fgf8ati282a/ti282a; rereatb210/tb210 standard conditions Long-pec endoderm ISH
Long-pec pharyngeal pouch 1 ISH
Long-pec pharyngeal pouch 2 ISH
Long-pec Not Detected pharyngeal pouch 3 ISH
Long-pec Not Detected pharyngeal pouch 4 ISH
Long-pec Not Detected pharyngeal pouch 5 ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
fgf8ati282a/ti282a; rereatb210/tb210 standard conditions Long-pec pharyngeal pouch malformed, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.