Fig. 5

Norton et al., 2005 - Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones
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Fig. 5

Floorplate differentiation fails in mol-/- but not in smu-/- embryos. Lateral (A-I) and dorsal (J-O) views of the trunk floorplate in 36 hpf (A-I) and 24 hpf (J-O) wild-type, mol-/- and smu-/- embryos. (A-O) Expression of floorplate differentiation markers col2a1, min1, min2, arx and ctgf is similar in wild-type and smu-/- embryos but expression is severely reduced or absent in the mol-/- embryos (despite the presence of floorplate cells, arrowhead in B). Although floorplate expression is retained, the somitic expression of arx and ctgf is lost in the smu-/- mutants (L,O). fp, floorplate; hy, hypochord; nc, notochord.

Expression Data
Anatomical Terms:
Stage Range: Prim-5 to Prim-25

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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