ZFIN ID: ZDB-GENE-030131-102
Gene Name: connective tissue growth factor a
Gene Symbol: ctgfa
Sequence Ontology ID : SO:0000704

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Previous Names: ctgf, hm:zeh1559, si:dkey-266k12.4, wu:fl25c03 (1), zCTGF-c20 (1), zgc:136644

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 10 publications
Directly Submitted Expression Data: 7 figures (12 images) from Thisse et al., 2005 [eu936]
  8 figures (24 images) from Rauch et al., 2003 [cegs2096]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  adaxial cell, axial vasculature, caudal fin, central canal (all 30) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns50 Small Deletion Exon 3 Frameshift, Premature Stop TALEN
el654 Small Deletion Unknown Unknown CRISPR
sa11839 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13699 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa25135 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: CRISPR1-ctgfa (2), CRISPR2-ctgfa (1), CRISPR3-ctgfa (1), CRISPR4-ctgfa (1), CRISPR5-ctgfa (1) (all 11) expand
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in: cardiac muscle progenitor cell migration to the midline involved in heart field formation, endoderm anterior region, endoderm antero-medial region, endoderm apoptotic process (all 17) expand
    DISEASE ASSOCIATED WITH ctgfa HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component extracellular region (more)
    Molecular Function insulin-like growth factor binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000867 (1)
  • InterPro:IPR000884 (1)
  • InterPro:IPR001007 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR006208 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR012395 (1)
  • InterPro:IPR036383 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01208 (1)
  • PROSITE:PS01225 (1)
  • PROSITE:PS50092 (1)
  • PROSITE:PS50184 (1)
  • PROSITE:PS51323 (1)
  • Pfam:PF00007 (1)
  • Pfam:PF00090 (1)
  • Pfam:PF00093 (1)
  • Pfam:PF00219 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ctgfa-001 (1) 2119
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ctgfa
    Tg(-1ctgfa:d2GFP), tg(ctgfa:egfp), tg(hsp70l:ctgfa-2a-egfp), tg2(ctgfa:egfp), tg2(hsp70l:ctgfa-2a-egfp) (all 6) expand
    MARKER RELATIONSHIPS
    ctgfaContained in: [BAC] DKEY-266K12 (1) (order this)
    ctgfaEncodes: [EST] cegs2096 (1) (order this), eu936 (1), fl25c03, zeh1559 (1)
    [cDNA] MGC:136644 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001015041 (1) 2119bp
    Genomic GenBank:BX323010 (1) 176396bp
    Select Tool
    Polypeptide UniProtKB:Q5RI33 (1) 345aa
    Sequence Clusters UniGene:42794 (1)
    Sequence Information (all 31)
    OTHER ctgfa GENE PAGES
  • Alliance (1)
  • Gene:321449 (1)
  • VEGA:OTTDARG00000006901 (1)
  • Ensembl(GRCz10):ENSDARG00000042934 (1)
  • ORTHOLOGY for ctgfa (Chr: 20)
    CITATIONS (56)