Gene

ccn2a

ID
ZDB-GENE-030131-102
Name
cellular communication network factor 2a
Symbol
ccn2a Nomenclature History
Previous Names
  • ctgf
  • ctgfa
  • hm:zeh1559
  • si:dkey-266k12.4
  • wu:fl25c03 (1)
  • zCTGF-c20 (1)
  • zgc:136644
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable heparin binding activity and integrin binding activity. Acts upstream of or within with a negative effect on definitive hemopoiesis. Acts upstream of or within several processes, including endoderm development; notochord development; and regeneration. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including digestive system; fin; head; mesoderm; and spinal cord. Orthologous to human CCN2 (cellular communication network factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
37 figures from 21 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccn2a Human Ortholog
No data available
Associated With ccn2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000867 Insulin-like growth factor-binding protein, IGFBP
Domain IPR001007 VWFC domain
Domain IPR006207 Cystine knot, C-terminal
Domain IPR006208 Glycoprotein hormone subunit beta
Domain IPR043973 CCN, TSP1 domain
Family IPR012395 IGFBP-related, CNN
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length CCN, TSP1 domain Cystine knot, C-terminal Glycoprotein hormone subunit beta Growth factor receptor cysteine-rich domain superfamily IGFBP-related, CNN Insulin-like growth factor-binding protein, IGFBP Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily VWFC domain
UniProtKB:Q3B7E1 249
UniProtKB:Q5RI33 345
UniProtKB:C1I1X9 305
UniProtKB:Q6T8L8 20
UniProtKB:Q567D8 249
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations