- Title
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STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
- Authors
- Dinarello, A., Betto, R.M., Diamante, L., Tesoriere, A., Ghirardo, R., Cioccarelli, C., Meneghetti, G., Peron, M., Laquatra, C., Tiso, N., Martello, G., Argenton, F.
- Source
- Full text @ Cell Death Discov
STAT3 regulates a subset of hypoxia-dependent genes. |
STAT3 physically interacts with HIF1α. |
Stat3 is necessary for Hif1α transcriptional activity. |
Stat3 and Hif1α cooperate in the nucleus for the transcription of Hif1α target genes. |
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