Fig. 1

Fig. 1. Protein structures of neuropathy-related Ars and Aimp. Domain structures of 17 Ars and 2 Aimp genes in zebrafish. Protein domains were annotated with different colors. GST, Glutathione S-transferase; EMAPII, Endothelial-Monocyte Activating Polypeptide II; UNE, unique sequences; WHEP, TrpRS(W) HisRS(H) GluProRS(EP)-specific domain; EcAsp_like, enzyme commission aspartyl_like; DHHA, Asp-His-His motif associated; tRNA_SAD, tRNA_second additional domain.

Fig. 2

Fig. 2. An expression heatmap of 14 ars and 2 aimp genes at 24 and 48 hpf. (A, C) An expression heatmap for all 16 genes at 24 hpf (A) and 48 hpf (C). (B, D) gars expression as representative images at 24 hpf (B) and 48 hpf (D). Scale bar = 200 μm. (refer to the list of abbreviations for the name of tissues).
Fig. 3

Fig. 3. An expression heatmap of 14 ars and 2 aimp genes at 3 and 4.5 dpf. (A, C) An expression heatmap for all 16 genes at 3 dpf (A) and 4.5 dpf (C). (B, D) gars expression as representative images at 3 dpf (B) and 4.5 dpf (D). Scale bar = 200 μm. (refer to the list of abbreviations for the name of tissues).
Fig. 4

Fig. 4. aimp1 is essential for the cerebrovascular formation. (A) Representative images of the hindbrain vasculatures of Tg(kdrl:EGFP) zebrafish embryos upon aimp1 MO knockdown and rescue by aimp1 mRNA expression at 52 hpf. (B) Quantitative analysis of lengths and branching points of central arteries in the hindbrain. Scale bar = 100 μm ∗, p < 0.05; ∗∗, p < 0.01; ∗∗∗, p < 0.001; ns, not significant. Values are means ± standard deviation.
Fig. S1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. S2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. S3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. S4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biochem. Biophys. Res. Commun.
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