Gene

aimp2

ID
ZDB-GENE-040426-2652
Name
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
Symbol
aimp2 Nomenclature History
Previous Names
  • wu:fc09d04
  • zgc:63976
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be involved in positive regulation of aminoacyl-tRNA ligase activity. Predicted to localize to aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alar plate midbrain region; head; immature eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aimp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukodystrophy, hypomyelinating, 17 618006
Associated With aimp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004046 Glutathione S-transferase, C-terminal
Domain IPR031889 AIMP2, lysyl-tRNA synthetase binding domain
Domain IPR041503 AIMP2, thioredoxin-like domain
Family IPR042360 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Homologous_superfamily IPR036282 Glutathione S-transferase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length AIMP2, lysyl-tRNA synthetase binding domain AIMP2, thioredoxin-like domain Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Glutathione S-transferase, C-terminal Glutathione S-transferase, C-terminal domain superfamily
UniProtKB:Q7T3C0 321
UniProtKB:A0A8M9PXA5 285
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations