ZFIN

ZFIN ID: ZDB-TGCONSTRCT-101007-1

ZFIN ID: ZDB-TGCONSTRCT-101007-1

CITATIONS (46 total)

Transgenic Construct Name:	Tg(ZM)
Transgenic Construct Symbol:	Tg(ZM)

Doggett, K., Morgan, K.J., Olthof, A.M., Mieruszynski, S., Williams, B.B., Garnham, A.L., Milevskiy, M.J.G., Whitehead, L., Coates, J., Buchert, M., O'Donoghue, R.J.J., Hall, T.E., Putoczki, T.L., Ernst, M., Sutherland, K.D., Kanadia, R.N., Heath, J.K. (2025) Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers. EMBO reports. :

Kikel-Coury, N.L., Green, L.A., Nichols, E.L., Zellmer, A.M., Pai, S., Hedlund, S.A., Marsden, K., Smith, C.J. (2021) Pioneer axons utilize a dcc signaling-mediated invasion brake to precisely complete their pathfinding odyssey. The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(31):6617-6636

Oltrabella, F., Jackson-Crawford, A., Yan, G., Rixham, S., Starborg, T., Lowe, M. (2021) IPIP27A cooperates with OCRL to support endocytic traffic in the zebrafish pronephric tubule. Human molecular genetics. 31(8):1183-1196

Gliozzi, M.L., Espiritu, E.B., Shipman, K.E., Rbaibi, Y., Long, K.R., Roy, N., Duncan, A.W., Lazzara, M.J., Hukriede, N.A., Baty, C.J., Weisz, O.A. (2019) Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model. Journal of the American Society of Nephrology : JASN. 31(1):67-83

Mondin, V.E., Ben El Kadhi, K., Cauvin, C., Jackson-Crawford, A., Bélanger, E., Decelle, B., Salomon, R., Lowe, M., Echard, A., Carréno, S. (2019) PTEN reduces endosomal PtdIns(4,5)P₂ in a phosphatase-independent manner via a PLC pathway. The Journal of cell biology. 218(7):2198-2214

Young, R.M., Ewan, K.B., Ferrer, V.P., Allende, M.L., Godovac-Zimmermann, J., Dale, T.C., Wilson, S.W. (2019) Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLIFE. 8:

Young, R.M., Hawkins, T.A., Cavodeassi, F., Stickney, H.L., Schwarz, Q., Lawrence, L.M., Wierzbicki, C., Cheng, B.Y., Luo, J., Ambrosio, E.M., Klosner, A., Sealy, I.M., Rowell, J., Trivedi, C.A., Bianco, I.H., Allende, M.L., Busch-Nentwich, E.M., Gestri, G., Wilson, S.W. (2019) Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLIFE. 8:

Drummond, B.E., Wingert, R.A. (2018) Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm.. Cancer cell & microenvironment. 5(1)

LLeras Forero, L., Narayanan, R., Huitema, L.F.A., VanBergen, M., Apschner, A., Peterson-Maduro, J., Logister, I., Valentin, G., Morelli, L.G., Oates, A., Schulte-Merker, S. (2018) Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock. eLIFE. 7

Kroeger, P.T., Drummond, B.E., Miceli, R., McKernan, M., Gerlach, G.F., Marra, A.N., Fox, A., McCampbell, K.K., Leshchiner, I., Rodriguez-Mari, A., BreMiller, R., Thummel, R., Davidson, A.J., Postlethwait, J., Goessling, W., Wingert, R.A. (2017) The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Developmental Biology. 428(1):148-163

Richter, S., Schulze, U., Tomançak, P., Oates, A.C. (2017) Small molecule screen in embryonic zebrafish using modular variations to target segmentation. Nature communications. 8:1901

Webster, K.A., Schach, U., Ordaz, A., Steinfeld, J.S., Draper, B.W., Siegfried, K.R. (2017) Dmrt1 is necessary for male sexual development in zebrafish. Developmental Biology. 422(1):33-46

De Leo, M.G., Staiano, L., Vicinanza, M., Luciani, A., Carissimo, A., Mutarelli, M., Di Campli, A., Polishchuk, E., Di Tullio, G., Morra, V., Levtchenko, E., Oltrabella, F., Starborg, T., Santoro, M., di Bernardo, D., Devuyst, O., Lowe, M., Medina, D.L., Ballabio, A., De Matteis, M.A. (2016) Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL. Nature cell biology. 18:839-50

Deshwar, A.R., Chng, S.C., Ho, L., Reversade, B., Scott, I.C. (2016) The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development. eLIFE. 5

Flanagan-Steet, H., Matheny, C., Petrey, A., Parker, J., Steet, R. (2016) Enzyme-specific differences in mannose phosphorylation between GlcNAc-1-phosphotransferase αβ and γ subunit deficient zebrafish support cathepsin proteases as early mediators of mucolipidosis pathology. Biochimica et biophysica acta. General subjects. 1860(9):1845-53

Gaston-Massuet, C., McCabe, M.J., Scagliotti, V., Young, R.M., Carreno, G., Gregory, L.C., Jayakody, S.A., Pozzi, S., Gualtieri, A., Basu, B., Koniordou, M., Wu, C.I., Bancalari, R.E., Rahikkala, E., Veijola, R., Lopponen, T., Graziola, F., Turton, J., Signore, M., Mousavy Gharavy, S.N., Charolidi, N., Sokol, S.Y., Andoniadou, C.L., Wilson, S.W., Merrill, B.J., Dattani, M.T., Martinez-Barbera, J.P. (2016) Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 113:E548-57

Park, H., Galbraith, R., Turner, T., Mehojah, J., Azuma, M. (2016) Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish. Scientific Reports. 6:32297

Ebarasi, L., Ashraf, S., Bierzynska, A., Gee, H.Y., McCarthy, H.J., Lovric, S., Sadowski, C.E., Pabst, W., Vega-Warner, V., Fang, H., Koziell, A., Simpson, M.A., Dursun, I., Serdaroglu, E., Levy, S., Saleem, M.A., Hildebrandt, F., Majumdar, A. (2015) Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. American journal of human genetics. 96(1):153-61

Merkes, C., Turkalo, T.K., Wilder, N., Park, H., Wenger, L.W., Lewin, S.J., Azuma, M. (2015) Ewing Sarcoma Ewsa Protein Regulates Chondrogenesis of Meckel's Cartilage through Modulation of Sox9 in Zebrafish. PLoS One. 10:e0116627

Oltrabella, F., Pietka, G., Ramirez, I.B., Mironov, A., Starborg, T., Drummond, I.A., Hinchliffe, K.A., Lowe, M. (2015) The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule. PLoS Genetics. 11:e1005058

Pfeiffer, C., Bach, M., Bauer, T., da Ponte, J.C., Schömig, E., Gründemann, D. (2015) Knockout of the ergothioneine transporter ETT in zebrafish results in increased 8-oxoguanine levels. Free radical biology & medicine. 83:178-85

Sidik, H., Talbot, W.S. (2015) A zinc finger protein that regulates oligodendrocyte specification, migration, and myelination in zebrafish. Development (Cambridge, England). 142(23):4119-28

Ay, A., Holland, J., Sperlea, A., Devakanmalai, G.S., Knierer, S., Sangervasi, S., Stevenson, A., Ozbudak, E.M. (2014) Spatial gradients of protein-level time delays set the pace of the traveling segmentation clock waves. Development (Cambridge, England). 141:4158-67

Jain, R.A., Bell, H., Lim, A., Chien, C.B., Granato, M. (2014) Mirror movement-like defects in startle behavior of zebrafish dcc mutants are caused by aberrant midline guidance of identified descending hindbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:2898-909

Lee, S., Page-McCaw, P., Gamse, J.T. (2014) Kctd12 and Ulk2 partner to regulate dendritogenesis and behavior in the habenular nuclei.. PLoS One. 9(10):1-7

Markmiller, S., Cloonan, N., Lardelli, R.M., Doggett, K., Keightley, M.C., Boglev, Y., Trotter, A.J., Ng, A.Y., Wilkins, S.J., Verkade, H., Ober, E.A., Field, H.A., Grimmond, S.M., Lieschke, G.J., Stainier, D.Y., and Heath, J.K. (2014) Minor class splicing shapes the zebrafish transcriptome during development. Proceedings of the National Academy of Sciences of the United States of America. 111(8):3062-3067

Rosenberg, A.F., Isaacman-Beck, J., Franzini-Armstrong, C., Granato, M. (2014) Schwann cells and deleted in colorectal carcinoma direct regenerating motor axons towards their original path. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:14668-81

Ay, A., Knierer, S., Sperlea, A., Holland, J., and Ozbudak, E.M. (2013) Short-lived Her proteins drive robust synchronized oscillations in the zebrafish segmentation clock. Development (Cambridge, England). 140(15):3244-3253

Zaucker, A., Mercurio, S., Sternheim, N., Talbot, W.S., and Marlow, F.L. (2013) notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish. Disease models & mechanisms. 6(5):1246-59

Clément, A., Solnica-Krezel, L., and Gould, K.L. (2012) Functional redundancy between Cdc14 phosphatases in zebrafish ciliogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(12):1911-1921

Coon, B.G., Hernandez, V., Madhivanan, K., Mukherjee, D., Hanna, C.B., Ramirez, I.B., Lowe, M., Beales, P.L., and Aguilar, R.C. (2012) The Lowe Syndrome Protein OCRL1 is Involved in Primary Cilia Assembly. Human molecular genetics. 21(8):1835-1847

Ramirez, I.B., Pietka, G., Jones, D.R., Divecha, N., Aliam, A., Baraban, S.C., Hurlstone, A.F., and Lowe, M. (2012) Impaired Neural Development in a Zebrafish Model for Lowe Syndrome. Human molecular genetics. 21(8):1744-1759

Schröter, C., Ares, S., Morelli, L.G., Isakova, A., Hens, K., Soroldoni, D., Gajewski, M., Jülicher, F., Maerkl, S.J., Deplancke, B., and Oates, A.C. (2012) Topology and dynamics of the zebrafish segmentation clock core circuit. PLoS Biology. 10(7):e1001364

Tobin, D.M., Roca, F.J., Oh, S.F., McFarland, R., Vickery, T.W., Ray, J.P., Ko, D.C., Zou, Y., Bang, N.D., Chau, T.T., Vary, J.C., Hawn, T.R., Dunstan, S.J., Farrar, J.J., Thwaites, G.E., King, M.C., Serhan, C.N., and Ramakrishnan, L. (2012) Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 148(3):434-446

Clément, A., Solnica-Krezel, L., and Gould, K.L. (2011) The Cdc14B phosphatase contributes to ciliogenesis in zebrafish. Development (Cambridge, England). 138(2):291-302

Rodriguez-Mari, A., Wilson, C., Titus, T.A., Cañestro, C., Bremiller, R.A., Yan, Y.L., Nanda, I., Johnston, A., Kanki, J.P., Gray, E.M., He, X., Spitsbergen, J., Schindler, D., and Postlethwait, J.H. (2011) Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish. PLoS Genetics. 7(3):e1001357

Taylor, R.W., Qi, J.Y., Talaga, A.K., Ma, T.P., Pan, L., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T. (2011) Asymmetric inhibition of ulk2 causes left-right differences in habenular neuropil formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(27):9869-9878

Pei, W., Kratz, L.E., Bernardini, I., Sood, R., Yokogawa, T., Dorward, H., Ciccone, C., Kelley, R.I., Anikster, Y., Burgess, H.A., Huizing, M., and Feldman, B. (2010) A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3. Development (Cambridge, England). 137(15):2587-2596

Schröter, C., and Oates, A.C. (2010) Segment Number and Axial Identity in a Segmentation Clock Period Mutant. Current biology : CB. 20(14):1254-1258

Tobin, D.M., Vary, J.C. Jr, Ray, J.P., Walsh, G.S., Dunstan, S.J., Bang, N.D., Hagge, D.A., Khadge, S., King, M.C., Hawn, T.R., Moens, C.B., and Ramakrishnan, L. (2010) The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans. Cell. 140(5):717-730

Gribble, S.L., Kim, H.S., Bonner, J., Wang, X., and Dorsky, R.I. (2009) Tcf3 inhibits spinal cord neurogenesis by regulating sox4a expression. Development (Cambridge, England). 136(5):781-789

Additional Citations (5):

Zebrafish Nomenclature Committee (2018) Nomenclature Data Curation (2018). Nomenclature Committee Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Zebrafish Nomenclature Committee (2011) Nomenclature Data Curation (active). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.