ZFIN

ZFIN ID: ZDB-GENE-990415-279

ZFIN ID: ZDB-GENE-990415-279

CITATIONS (75 total)

Gene Name:	wingless-type MMTV integration site family, member 8b
Gene Symbol:	wnt8b

LaCoursiere, C.M., Ullmann, J.F.P., Koh, H.Y., Turner, L., Baker, C.M., Robens, B., Shao, W., Rotenberg, A., McGraw, C.M., Poduri, A.H. (2024) Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitability. iScience. 27:110172110172

Brown-Panton, C.A., Sabour, S., Zoidl, G.S.O., Zoidl, C., Tabatabaei, N., Zoidl, G.R. (2023) Gap junction Delta-2b (gjd2b/Cx35.1) depletion causes hyperopia and visual-motor deficiencies in the zebrafish. Frontiers in cell and developmental biology. 11:11502731150273

Ha, T.T., Burgess, R., Newman, M., Moey, C., Mandelstam, S.A., Gardner, A.E., Ivancevic, A.M., Pham, D., Kumar, R., Smith, N., Patel, C., Malone, S., Ryan, M.M., Calvert, S., van Eyk, C.L., Lardelli, M., Berkovic, S.F., Leventer, R.J., Richards, L.J., Scheffer, I.E., Gecz, J., Corbett, M.A. (2023) Aicardi Syndrome Is a Genetically Heterogeneous Disorder. Genes. 14(8):

Li, Y., Wang, C., Zhang, L., Chen, B., Mo, Y., Zhang, J. (2022) Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier. Fluids and barriers of the CNS. 19:40

Naraine, R., Iegorova, V., Abaffy, P., Franek, R., Soukup, V., Psenicka, M., Sindelka, R. (2022) Evolutionary conservation of maternal RNA localization in fishes and amphibians revealed by TOMO-Seq. Developmental Biology. 489:146-160

Westphal, M., Panza, P., Kastenhuber, E., Wehrle, J., Driever, W. (2022) Wnt/β-catenin signaling promotes neurogenesis in the diencephalospinal dopaminergic system of embryonic zebrafish. Scientific Reports. 12:1030

Jung, J., Kim, E., Rhee, M. (2021) Kapd Is Essential for Specification of the Dopaminergic Neurogenesis in Zebrafish Embryos. Molecules and cells. 44(4):233-244

Lin, Z., Luo, M., Zhou, B., Liu, Y., Sun, H. (2021) CFTR regulates embryonic T lymphopoiesis via Wnt signaling in zebrafish. Immunology Letters. 234:47-53

Cang, Z., Nie, Q. (2020) Inferring spatial and signaling relationships between cells from single cell transcriptomic data. Nature communications. 11:2084

Zhang, Q., Zhang, C., Zhang, C., Peng, G. (2020) Wnt Signaling Regulates Ipsilateral Pathfinding in the Zebrafish Forebrain through slit3. Neuroscience. 449:9-20

Grainger, S., Richter, J., Palazón, R.E., Pouget, C., Lonquich, B., Wirth, S., Grassme, K.S., Herzog, W., Swift, M.R., Weinstein, B.M., Traver, D., Willert, K. (2016) Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Reports. 17:1595-1606

Duncan, R.N., Panahi, S., Piotrowski, T., Dorsky, R.I. (2015) Identification of Wnt Genes Expressed in Neural Progenitor Zones during Zebrafish Brain Development. PLoS One. 10:e0145810

Patil, P., Kibiryeva, N., Uechi, T., Marshall, J., O'Brien, J.E., Artman, M., Kenmochi, N., Bittel, D.C. (2015) scaRNAs Regulate Splicing and Vertebrate Heart Development. Biochimica et biophysica acta. Molecular basis of disease. 1852(8):1619-29

Dirian, L., Galant, S., Coolen, M., Chen, W., Bedu, S., Houart, C., Bally-Cuif, L., Foucher, I. (2014) Spatial Regionalization and Heterochrony in the Formation of Adult Pallial Neural Stem Cells. Developmental Cell. 30(2):123-36

Holly, V.L., Widen, S.A., Famulski, J.K., and Waskiewicz, A.J. (2014) Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development. Developmental Biology. 388(2):192-204

Lu, F.I., Sun, Y.H., Wei, C.Y., Thisse, C., Thisse, B. (2014) Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway. Nature communications. 5:5368

Wan, J., Zhao, X.F., Vojtek, A., Goldman, D. (2014) Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration. Cell Reports. 9(1):285-97

Hofmeister, W., and Key, B. (2013) Frizzled-3a and Wnt-8b genetically interact during forebrain commissural formation in embryonic zebrafish. Brain research. 1506:25-34

Wolf, A., and Ryu, S. (2013) Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development (Cambridge, England). 140(8):1762-1773

Carlin, D., Sepich, D., Grover, V.K., Cooper, M.K., Solnica-Krezel, L., and Inbal, A. (2012) Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling. Development (Cambridge, England). 139(14):2614-2624

Mattes, B., Weber, S., Peres, J., Chen, Q., Davidson, G., Houart, C., and Scholpp, S. (2012) Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain. Neural Development. 7(1):12

Hong, S.K., and Dawid, I.B. (2011) The transcriptional mediator component med12 is required for hindbrain boundary formation. PLoS One. 6(4):e19076

Kagermeier-Schenk, B., Wehner, D., Ozhan-Kizil, G., Yamamoto, H., Li, J., Kirchner, K., Hoffmann, C., Stern, P., Kikuchi, A., Schambony, A., and Weidinger, G. (2011) Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization. Developmental Cell. 21(6):1129-43

Lu, F.I., Thisse, C., and Thisse, B. (2011) Identification and mechanism of regulation of the zebrafish dorsal determinant. Proceedings of the National Academy of Sciences of the United States of America. 108(38):15876-80

Ramachandran, R., Zhao, X.F., and Goldman, D. (2011) Ascl1a/Dkk/ beta -catenin signaling pathway is necessary and glycogen synthase kinase-3 beta inhibition is sufficient for zebrafish retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 108(38):15858-63

Yee, N.S., Zhou, W., and Liang, I.C. (2011) Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer. Disease models & mechanisms. 4(2):240-254

Zhao, X., Kuja-Panula, J., Rouhiainen, A., Chen, Y.C., Panula, P., and Rauvala, H. (2011) High mobility group box-1 (HMGB1; amphoterin) is required for zebrafish brain development. The Journal of biological chemistry. 286(26):23200-13

Danesin, C., Peres, J.N., Johansson, M., Snowden, V., Cording, A., Papalopulu, N., and Houart, C. (2009) Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1. Developmental Cell. 16(4):576-587

Paridaen, J.T., Danesin, C., Elas, A.T., van de Water, S., Houart, C., and Zivkovic, D. (2009) Apc1 is required for maintenance of local brain organizers and dorsal midbrain survival. Developmental Biology. 331(2):101-112

Scholpp, S., Delogu, A., Gilthorpe, J., Peukert, D., Schindler, S., and Lumsden, A. (2009) Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus. Proceedings of the National Academy of Sciences of the United States of America. 106(47):19895-19900

Shima, T., Znosko, W., and Tsang, M. (2009) The characterization of a zebrafish mid-hindbrain mutant, mid-hindbrain gone (mgo). Developmental Dynamics : an official publication of the American Association of Anatomists. 238(4):899-907

Viktorin, G., Chiuchitu, C., Rissler, M., Varga, Z.M., and Westerfield, M. (2009) Emx3 is required for the differentiation of dorsal telencephalic neurons. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(8):1984-1998

Russek-Blum, N., Gutnick, A., Nabel-Rosen, H., Blechman, J., Staudt, N., Dorsky, R.I., Houart, C., and Levkowitz, G. (2008) Dopaminergic neuronal cluster size is determined during early forebrain patterning. Development (Cambridge, England). 135(20):3401-3413

Veien, E.S., Rosenthal, J.S., Kruse-Bend, R.C., Chien, C.B., and Dorsky, R.I. (2008) Canonical Wnt signaling is required for the maintenance of dorsal retinal identity. Development (Cambridge, England). 135(24):4101-4111

Carl, M., Bianco, I.H., Bajoghli, B., Aghaallaei, N., Czerny, T., and Wilson, S.W. (2007) Wnt/Axin1/beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries. Neuron. 55(3):393-405

Garriock, R.J., Warkman, A.S., Meadows, S.M., D'Agostino, S., and Krieg, P.A. (2007) Census of vertebrate Wnt genes: Isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(5):1249-1258

Hans, S., and Westerfield, M. (2007) Changes in retinoic acid signaling alter otic patterning. Development (Cambridge, England). 134(13):2449-2458

Jeong, J.Y., Einhorn, Z., Mathur, P., Chen, L., Lee, S., Kawakami, K., and Guo, S. (2007) Patterning the zebrafish diencephalon by the conserved zinc-finger protein Fezl. Development (Cambridge, England). 134(1):127-136

Kim, H.S., Shin, J., Kim, S.H., Chun, H.S., Kim, J.D., Kim, Y.S., Kim, M.J., Rhee, M., Yeo, S.Y., and Huh, T.L. (2007) Eye field requires the function of Sfrp1 as a Wnt antagonist. Neuroscience letters. 414(1):26-29

Scholpp, S., Foucher, I., Staudt, N., Peukert, D., Lumsden, A., and Houart, C. (2007) Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon. Development (Cambridge, England). 134(17):3167-3176

Staudt, N., and Houart, C. (2007) The prethalamus is established during gastrulation and influences diencephalic regionalization. PLoS Biology. 5(4):e69

Eroglu, B., Wang, G., Tu, N., Sun, X., and Mivechi, N.F. (2006) Critical role of Brg1 member of the SWI/SNF chromatin remodeling complex during neurogenesis and neural crest induction in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2722-2735

Lee, J.E., Wu, S.F., Goering, L.M., and Dorsky, R.I. (2006) Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis. Development (Cambridge, England). 133(22):4451-4461

Peng, G., and Westerfield, M. (2006) Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development (Cambridge, England). 133(16):3191-3200

Cavodeassi, F., Carreira-Barbosa, F., Young, R., Concha, M., Allende, M.L., Houart, C., Tada, M., and Wilson, S. (2005) Early Stages of Zebrafish Eye Formation Require the Coordinated Activity of Wnt11, Fz5, and the Wnt/Catenin Pathway. Neuron. 47(1):43-56

Correa, R.G., Matsui, T., Tergaonkar, V., Rodriguez-Esteban, C., Izpisúa Belmonte, J.C., and Verma, I.M. (2005) Zebrafish IkappaB Kinase 1 Negatively Regulates NF-kappaB Activity. Current biology : CB. 15(14):1291-1295

Matsui, T., Raya, A., Kawakami, Y., Callol-Massot, C., Capdevila, J., Rodriguez-Esteban, C., Izpisúa Belmonte, J.C. (2005) Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes & Development. 19(1):164-175

Kapsimali, M., Caneparo, L., Houart, C., and Wilson, S.W. (2004) Inhibition of Wnt/Axin/{beta}-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity. Development (Cambridge, England). 131(23):5923-5933

Nambiar, R.M., and Henion, P.D. (2004) Sequential antagonism of early and late Wnt-signaling by zebrafish colgate promotes dorsal and anterior fates. Developmental Biology. 267(1):165-80

Riley, B.B., Chiang, M.Y., Storch, E.M., Heck, R., Buckles, G.R., and Lekven, A.C. (2004) Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(2):278-291

Thorpe, C.J., and Moon, R.T. (2004) nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development. Development (Cambridge, England). 131(12):2899-2909

Handrigan, G.R. (2003) Concordia discors: duality in the origin of the vertebrate tail. Journal of anatomy. 202(3):255-267

Houart, C., Caneparo, L., Heisenberg, C.P., Barth, K.A., Take-uchi, M., and Wilson, S.W. (2002) Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron. 35(2):255-265

Kim, S.-H., Shin, J., Park, H.-C., Yeo, S.-Y., Hong, S.-K., Han, S., Rhee, M., Kim, C.-H., Chitnis, A.B., and Huh, T.-L. (2002) Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish. Development (Cambridge, England). 129(19):4443-4455

Reim, G. and Brand, M. (2002) spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development. Development (Cambridge, England). 129(4):917-933

Hashimoto, H., Itoh, M., Yamanaka, Y., Yamashita, S., Shimizu, T., Solnica-Krezel, L., Hibi, M., and Hirano, T. (2000) Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation. Developmental Biology. 217(1):138-152

Schubert, M., Holland, L.Z., Panopoulou, G.D., Lehrach, H., and Holland, N.D. (2000) Characterization of amphioxus AmphiWnt8: insights into the evolution of patterning of the embryonic dorsoventral axis. Evolution & development. 2(2):85-92

Kelly, G.M., Greenstein, P., Erezyilmaz, D.F., and Moon, R.T. (1995) Zebrafish wnt8 and wnt8b share a common activity but are involved in distinct developmental pathways. Development (Cambridge, England). 121:1787-1799

Additional Citations (17):

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2016) Automated addition of links from ZFIN gene pages to SignaFish. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.