ZFIN

ZFIN ID: ZDB-GENE-030314-1

ZFIN ID: ZDB-GENE-030314-1

CITATIONS (37 total)

Gene Name:	cholinergic receptor, muscarinic 2a
Gene Symbol:	chrm2a

Baker, C.E., Marta, A.G., Zimmerman, N.D., Korade, Z., Mathy, N.W., Wilton, D., Simeone, T., Kochvar, A., Kramer, K.L., Stessman, H.A.F., Shibata, A. (2024) CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression. Biomolecules. 14(8):

Yan, J., Fang, L., Ni, A., Xi, M., Li, J., Zhou, X., Qian, Q., Wang, Z.J., Wang, X., Wang, H. (2024) Long-Term Neurotoxic Effects and Alzheimer's Disease Risk of Early EHDPP Exposure in Zebrafish: Insights from Molecular Mechanisms to Adult Pathology. Environmental science & technology. 58(43):19152-19164

Eachus, H., Oberski, L., Paveley, J., Bacila, I., Ashton, J.P., Esposito, U., Seifuddin, F., Pirooznia, M., Elhaik, E., Placzek, M., Krone, N., Cunliffe, V.T. (2023) Glucocorticoid Receptor regulates protein chaperone, circadian clock and affective disorder genes in the zebrafish brain. Disease models & mechanisms. 16(9):

Siregar, P., Audira, G., Feng, L.Y., Lee, J.H., Santoso, F., Yu, W.H., Lai, Y.H., Li, J.H., Lin, Y.T., Chen, J.R., Hsiao, C.D. (2021) Pharmaceutical Assessment Suggests Locomotion Hyperactivity in Zebrafish Triggered by Arecoline Might Be Associated with Multiple Muscarinic Acetylcholine Receptors Activation. toxins. 13(4):

Jia, S., Wu, X., Wu, Y., Cui, X., Tao, B., Zhu, Z., Hu, W. (2020) Multiple Developmental Defects in sox11a Mutant Zebrafish with Features of Coffin-Siris Syndrome. International journal of biological sciences. 16:3039-3049

Burczyk, M.S., Burkhalter, M.D., Tena, T.C., Grisanti, L.A., Kauk, M., Matysik, S., Donow, C., Kustermann, M., Rothe, M., Cui, Y., Raad, F., Laue, S., Moretti, A., Zimmermann, W.H., Wess, J., Kühl, M., Hoffmann, C., Tilley, D.G., Philipp, M. (2019) Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI insight. 4(20):

Wang, M., Chen, Y., Zhu, M., Xu, B., Guo, W., Lyu, Y., Zhang, C. (2019) Pharmacological modulation of melanocortin-4 receptor by melanocortin receptor accessory protein 2 in Nile tilapia. General and comparative endocrinology. 282:113219

Zang, L., Shimada, Y., Nakayama, H., Chen, W., Okamoto, A., Koide, H., Oku, N., Dewa, T., Shiota, M., Nishimura, N. (2019) Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus. Frontiers in genetics. 10:693

Arcanjo, C., Armant, O., Floriani, M., Cavalie, I., Camilleri, V., Simon, O., Orjollet, D., Adam-Guillermin, C., Gagnaire, B. (2018) Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages. Aquatic toxicology (Amsterdam, Netherlands). 200:114-126

Pedersen, J.E., Bergqvist, C.A., Larhammar, D. (2018) Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates. eNeuro. 5(5):

Skarsfeldt, M.A., Bomholtz, S.H., Lundegaard, P.R., Lopez-Izquierdo, A., Tristani-Firouzi, M., Bentzen, B.H. (2018) Atrium-specific ion channels in the zebrafish-A role of I_KACh in atrial repolarization.. Acta physiologica (Oxford, England). 223(3):e13049

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902

Seo, J.S., Kim, M.S., Park, E.M., Ahn, S.J., Kim, N.Y., Jung, S.H., Kim, J.W., Lee, H.H., and Chung, J.K. (2009) Cloning and characterization of muscarinic receptor genes from the nile tilapia (Oreochromis niloticus). Molecules and cells. 27(3):383-390

Steele, S.L., Lo, K.H., Li, V.W., Cheng, S.H., Ekker, M., and Perry, S.F. (2009) Loss of M2 muscarinic receptor function inhibits development of hypoxic bradycardia and alters cardiac {beta}-adrenergic sensitivity in larval zebrafish Danio rerio. American journal of physiology. Regulatory, integrative and comparative physiology. 297(2):R412-R420

Hsieh, D.J.Y. and Liao, C.F. (2002) Zebrafish M2 muscarinic acetylcholine receptor: cloning, pharmacological characterization, expression patterns and roles in embryonic bradycardia. British journal of pharmacology. 137(6):782-792

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (20):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.