ZFIN

ZFIN ID: ZDB-GENE-030131-1819

ZFIN ID: ZDB-GENE-030131-1819

CITATIONS (63 total)

Gene Name:	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
Gene Symbol:	nfkbiab

Cao, Y., Xu, F., Xia, Q., Liu, K., Lin, H., Zhang, S., Zhang, Y. (2024) The Peptide LLTRAGL Derived from Rapana venosa Exerts Protective Effect against Inflammatory Bowel Disease in Zebrafish Model by Regulating Multi-Pathways. Marine drugs. 22(3):

Zhao, Y., Lv, H., Yu, C., Liang, J., Yu, H., Du, Z., Zhang, R. (2024) Systemic inhibition of mitochondrial fatty acid β-oxidation impedes zebrafish ventricle regeneration. Biochimica et biophysica acta. Molecular basis of disease. 1870(7):167442

Rosa, I.F., Peçanha, A.P.B., Carvalho, T.R.B., Alexandre, L.S., Ferreira, V.G., Doretto, L.B., Souza, B.M., Nakajima, R.T., da Silva, P., Barbosa, A.P., Gomes-de-Pontes, L., Bomfim, C.G., Machado-Santelli, G.M., Condino-Neto, A., Guzzo, C.R., Peron, J.P.S., Andrade-Silva, M., Câmara, N.O.S., Garnique, A.M.B., Medeiros, R.J., Ferraris, F.K., Barcellos, L.J.G., Correia-Junior, J.D., Galindo-Villegas, J., Machado, M.F.R., Castoldi, A., Oliveira, S.L., Costa, C.C., Belo, M.A.A., Galdino, G., Sgro, G.G., Bueno, N.F., Eto, S.F., Veras, F.P., Fernandes, B.H.V., Sanches, P.R.S., Cilli, E.M., Malafaia, G., Nóbrega, R.H., Garcez, A.S., Carrilho, E., Charlie-Silva, I. (2023) Photobiomodulation Reduces the Cytokine Storm Syndrome Associated with COVID-19 in the Zebrafish Model. International Journal of Molecular Sciences. 24(7):

Wu, C., Zhang, W., Luo, Y., Cheng, C., Wang, X., Jiang, Y., Li, S., Luo, L., Yang, Y. (2023) Zebrafish ppp1r21 mutant as a model for the study of primary biliary cholangitis. Journal of genetics and genomics = Yi chuan xue bao. 50(12):1004-1013

Yehuda, H., Madrer, N., Goldberg, D., Soreq, H., Meerson, A. (2023) Inversely Regulated Inflammation-Related Processes Mediate Anxiety-Obesity Links in Zebrafish Larvae and Adults. Cells. 12(13):

Zhang, T., Alonzo, I., Stubben, C., Geng, Y., Herdman, C., Chandler, N., Doane, K.P., Pluimer, B.R., Trauger, S.A., Peterson, R.T. (2023) A zebrafish model of Combined Saposin Deficiency identifies acid sphingomyelinase as a potential therapeutic target. Disease models & mechanisms. 16(7):

Brandão, A.S., Borbinha, J., Pereira, T., Brito, P.H., Lourenço, R., Bensimon-Brito, A., Jacinto, A. (2022) A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration. eLIFE. 11

Chatterjee, A., Maity, S., Banerjee, S., Dutta, S., Adhikari, M., Guchhait, R., Biswas, C., De, S., Pramanick, K. (2022) Toxicological impacts of nanopolystyrene on zebrafish oocyte with insight into the mechanism of action: An expression-based analysis. The Science of the total environment. 830:154796

Wasana, W.P., Senevirathne, A., Nikapitiya, C., Eom, T.Y., Lee, Y., Lee, J.S., Kang, D.H., Oh, C., De Zoysa, M. (2021) A Novel Pseudoalteromonas xiamenensis Marine Isolate as a Potential Probiotic: Anti-Inflammatory and Innate Immune Modulatory Effects against Thermal and Pathogenic Stresses. Marine drugs. 19(12):

Chen, M., Luo, Y., Xu, J., Chang, M.X., Liu, J.X. (2019) Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival. Frontiers in immunology. 10:2599

Espenschied, S.T., Cronan, M.R., Matty, M.A., Mueller, O., Redinbo, M.R., Tobin, D.M., Rawls, J.F. (2019) Epithelial delamination is protective during pharmaceutical-induced enteropathy. Proceedings of the National Academy of Sciences of the United States of America. 116(34):16961-16970

Kumari, Y., Choo, B.K.M., Shaikh, M.F., Othman, I. (2019) Melatonin receptor agonist Piper betle L. ameliorates dexamethasone-induced early life stress in adult zebrafish. Experimental and Therapeutic Medicine. 18:1407-1416

Lin, W., Guo, H., Wang, L., Zhang, D., Wu, X., Li, L., Qiu, Y., Yang, L., Li, D., Tang, R. (2019) Waterborne microcystin-LR exposure induced chronic inflammatory response via MyD88-dependent toll-like receptor signaling pathway in male zebrafish. The Science of the total environment. 702:134969

Luo, L., Zhou, J., Zhao, H., Fan, M., Gao, W. (2019) The anti-inflammatory effects of formononetin and ononin on lipopolysaccharide-induced zebrafish models based on lipidomics and targeted transcriptomics. Metabolomics : Official journal of the Metabolomic Society. 15:153

Mishra, R., Sehring, I., Cederlund, M., Mulaw, M., Weidinger, G. (2019) NF-κB Signaling Negatively Regulates Osteoblast Dedifferentiation during Zebrafish Bone Regeneration. Developmental Cell. 52(2):167-182.e7

Murdoch, C.C., Espenschied, S.T., Matty, M.A., Mueller, O., Tobin, D.M., Rawls, J.F. (2019) Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization. PLoS pathogens. 15:e1007381

Zhang, Y., Takagi, N., Yuan, B., Zhou, Y., Si, N., Wang, H., Yang, J., Wei, X., Zhao, H., Bian, B. (2019) The protection of indolealkylamines on LPS-induced inflammation in zebrafish. Journal of ethnopharmacology. 243:112122

Zhou, J., Gu, X., Fan, X., Zhou, Y., Wang, H., Si, N., Yang, J., Bian, B., Zhao, H. (2019) Anti-inflammatory and Regulatory Effects of Huanglian Jiedu Decoction on Lipid Homeostasis and the TLR4/MyD88 Signaling Pathway in LPS-Induced Zebrafish. Frontiers in Physiology. 10:1241

Cao, L., Wu, X.M., Hu, Y.W., Xue, N.N., Nie, P., Chang, M.X. (2018) The discrepancy function of NLRC5 isoforms in antiviral and antibacterial immune responses. Developmental and comparative immunology. 84:153-163

Jurynec, M.J., Sawitzke, A.D., Beals, T.C., Redd, M.J., Stevens, J., Otterud, B., Leppert, M.H., Grunwald, D.J. (2018) A hyperactivating proinflammatory RIPK2 allele associated with early-onset osteoarthritis. Human molecular genetics. 27(13):2383-2391

Wei, Y., Huang, L., Cao, J., Wang, C., Yan, J. (2018) Dietary Safety Assessment of Flk1-Transgenic Fish. Frontiers in Physiology. 9:8

Yang, F., Qiu, W., Li, R., Hu, J., Luo, S., Zhang, T., He, X., Zheng, C. (2018) Genome-wide identification of the interactions between key genes and pathways provide new insights into the toxicity of bisphenol F and S during early development in zebrafish. Chemosphere. 213:559-567

Zou, Q., Gang, K., Yang, Q., Liu, X., Tang, X., Lu, H., He, J., Luo, L. (2018) The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish. The Journal of biological chemistry. 293(31):11971-11983

Guo, S.N., Zheng, J.L., Yuan, S.S., Zhu, Q.L., Wu, C.W. (2017) Immunosuppressive effects and associated compensatory responses in zebrafish after full life-cycle exposure to environmentally relevant concentrations of cadmium. Aquatic toxicology (Amsterdam, Netherlands). 188:64-71

Hidasi, A.O., Groh, K.J., Suter, M.J., Schirmer, K. (2017) Clobetasol propionate causes immunosuppression in zebrafish (Danio rerio) at environmentally relevant concentrations. Ecotoxicology and environmental safety. 138:16-24

Hu, Y.W., Wu, X.M., Ren, S.S., Cao, L., Nie, P., Chang, M.X. (2017) NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway. Scientific Reports. 7:2979

Kuri, P., Ellwanger, K., Kufer, T.A., Leptin, M., Bajoghli, B. (2017) A high-sensitivity, bi-directional reporter to monitor NF-κB activity in cell culture and zebrafish in real-time. Journal of Cell Science. 130(3):648-657

Rauwerda, H., Pagano, J.F., de Leeuw, W.C., Ensink, W., Nehrdich, U., de Jong, M., Jonker, M., Spaink, H.P., Breit, T.M. (2017) Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. BMC Genomics. 18:287

Zheng, J.L., Yuan, S.S., Wu, C.W., Lv, Z.M., Zhu, A.Y. (2017) Circadian time-dependent antioxidant and inflammatory responses to acute cadmium exposure in the brain of zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 182:113-119

Zheng, J.L., Yuan, S.S., Wu, C.W., Lv, Z.M. (2016) Acute exposure to waterborne cadmium induced oxidative stress and immunotoxicity in the brain, ovary and liver of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 180:36-44

Dai, Z., Wang, H., Jin, X., Wang, H., He, J., Liu, M., Yin, Z., Sun, Y., Lou, Q. (2015) Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish. American journal of physiology. Endocrinology and metabolism. 308(10):E849-59

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Karra, R., Knecht, A.K., Kikuchi, K., Poss, K.D. (2015) Myocardial NF-κB activation is essential for zebrafish heart regeneration. Proceedings of the National Academy of Sciences of the United States of America. 112(43):13255-60

Kovács, R., Csenki, Z., Bakos, K., Urbányi, B., Horváth, Á., Garaj-Vrhovac, V., Gajski, G., Gerić, M., Negreira, N., López de Alda, M., Barceló, D., Heath, E., Kosjek, T., Žegura, B., Novak, M., Zajc, I., Baebler, Š., Rotter, A., Ramšak, Ž., Filipič, M. (2015) Assessment of toxicity and genotoxicity of low doses of 5-fluorouracil in zebrafish (Danio rerio) two-generation study. Water research. 77:201-212

Xue, Y., Gao, S., Liu, F. (2015) Genome-wide Analysis of the Zebrafish Klf Family Identifies Two Genes important for Erythroid Maturation. Developmental Biology. 403(2):115-27

Gao, R., Huang, Y., Huang, X., Guan, L., Wei, S., Zhou, Y., Qin, Q. (2014) Molecular cloning and characterization of two types of IkappaBalpha orthologues in orange-spotted grouper, Epinephelus coioides. Fish & shellfish immunology. 38:101-10

Hiolski, E.M., Kendrick, P.S., Frame, E.R., Myers, M.S., Bammler, T.K., Beyer, R.P., Farin, F.M., Wilkerson, H.W., Smith, D.R., Marcinek, D.J., Lefebvre, K.A. (2014) Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS. Aquatic toxicology (Amsterdam, Netherlands). 155C:151-159

Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902

Encinas, P., Garcia-Valtanen, P., Chinchilla, B., Gomez-Casado, E., Estepa, A., and Coll, J. (2013) Identification of Multipath Genes Differentially Expressed in Pathway-Targeted Microarrays in Zebrafish Infected and Surviving Spring Viremia Carp Virus (SVCV) Suggest Preventive Drug Candidates. PLoS One. 8(9):e73553

Liu, C., Xu, H., Lam, S.H., and Gong, Z. (2013) Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study. PLoS One. 8(12):e83954

Kanther, M., Sun, X., Mühlbauer, M., Mackey, L.C., Flynn, E.J., Bagnat, M., Jobin, C., and Rawls, J.F. (2011) Microbial colonization induces dynamic temporal and spatial patterns of NF-kappaB activation in the zebrafish digestive tract. Gastroenterology. 141(1):197-207

Watzke, J., Schirmer, K., and Scholz, S. (2007) Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio). Fish & shellfish immunology. 23(4):901-905

Correa, R.G., Matsui, T., Tergaonkar, V., Rodriguez-Esteban, C., Izpisúa Belmonte, J.C., and Verma, I.M. (2005) Zebrafish IkappaB Kinase 1 Negatively Regulates NF-kappaB Activity. Current biology : CB. 15(14):1291-1295

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Correa, R.G., Tergaonkar, V., Ng, J.K., Dubova, I., Izpisúa Belmonte, J.C., and Verma, I.M. (2004) Characterization of NF-kappa B/I kappa B proteins in zebra fish and their involvement in notochord development. Molecular and cellular biology. 24(12):5257-5268

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (17):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.