Publication	Data		Fish	Anatomy
Shao et al., 2022	Fig. 2		cyp2r1ihb153/ihb153	blood glucose increased amount, abnormal blood insulin decreased amount, abnormal
Peng et al., 2017	Fig. 2		cyp2r1ihb152/ihb152 ,   cyp2r1ihb153/ihb153	liver cyp2r1 expression increased amount, abnormal whole organism decreased size, abnormal
	Fig. 3		cyp2r1ihb153/ihb153	female organism lipid increased amount, abnormal male organism lipid increased amount, abnormal pleuroperitoneal cavity fat cell increased amount, abnormal subcutaneous fat increased amount, abnormal visceral fat increased amount, abnormal
	Fig. 4		cyp2r1ihb153/ihb153	whole organism decreased length, abnormal whole organism decreased weight, abnormal whole organism lipid increased amount, abnormal
	Fig. 5		cyp2r1ihb153/ihb153	visceral fat ppargc1a expression decreased amount, abnormal visceral fat Ab1-ppargc1a labeling decreased amount, abnormal
	Fig. 6		cyp2r1ihb153/ihb153	visceral fat esrra expression decreased amount, abnormal visceral fat mcu expression decreased amount, abnormal visceral fat mrpl15 expression decreased amount, abnormal visceral fat mrpl2 expression decreased amount, abnormal visceral fat mrps10 expression decreased amount, abnormal visceral fat mtfp1 expression decreased amount, abnormal visceral fat nrf1 expression decreased amount, abnormal visceral fat pparg expression increased amount, abnormal visceral fat slc25a20 expression decreased amount, abnormal visceral fat ucp1 expression decreased amount, abnormal visceral fat Ab1-mt-co1 labeling decreased amount, abnormal visceral fat Ab3-cox4 labeling decreased amount, abnormal visceral fat mitochondrion decreased amount, abnormal visceral fat mitochondrion decreased functionality, abnormal visceral fat mitochondrion membrane potential, abnormal
	Fig. S2		cyp2r1ihb153/ihb153	liver cyp24a1 expression decreased amount, abnormal liver cyp27a1.4 expression increased amount, abnormal liver cyp27b1 expression increased amount, abnormal
	Fig. S5		cyp2r1ihb153/ihb153	hypophysis gh1 expression increased amount, abnormal liver ghra expression increased amount, abnormal liver igf1 expression increased amount, abnormal liver ab3-stat5 labeling decreased amount, abnormal visceral fat ghra expression increased amount, abnormal visceral fat igf1 expression increased amount, abnormal
	Fig. S6		cyp2r1ihb153/ihb153	liver Ab1-ppargc1a labeling increased amount, abnormal
	Fig. S7		cyp2r1ihb153/ihb153	liver Ab1-mt-co1 labeling increased amount, abnormal liver Ab3-cox4 labeling increased amount, abnormal
	Table 1		cyp2r1ihb153/ihb153	blood plasma D3 vitamins decreased amount, abnormal blood plasma fatty acid increased amount, abnormal liver D3 vitamins decreased amount, abnormal visceral fat D3 vitamins decreased amount, abnormal
	Table S1		cyp2r1ihb153/ihb153	whole organism decreased length, abnormal whole organism decreased weight, abnormal
Cortes et al., 2015	Fig. 4		cyp2r1zf734/zf734 ,   WT + MO1-cyp2r1 + MO2-cyp2r1	smoothened signaling pathway disrupted, abnormal ventral wall of dorsal aorta ptch2 expression decreased amount, abnormal ventral wall of dorsal aorta runx1 expression decreased amount, abnormal