ZFIN Publication List

ZFIN ID: ZDB-ATB-081002-54

CITATIONS (127 total)

Antibody Name: Ab-S46

Auman, H.J., Fernandes, I.H., Berríos-Otero, C.A., Colombo, S., Yelon, D. (2023) Zebrafish smarcc1a mutants reveal requirements for BAF chromatin remodeling complexes in distinguishing the atrioventricular canal from the cardiac chambers. Developmental Dynamics : an official publication of the American Association of Anatomists. 253(1):157-172

Gafranek, J.T., D'Aniello, E., Ravisankar, P., Thakkar, K., Vagnozzi, R.J., Lim, H.W., Salomonis, N., Waxman, J.S. (2023) Sinus venosus adaptation models prolonged cardiovascular disease and reveals insights into evolutionary transitions of the vertebrate heart. Nature communications. 14:55095509

Hofeichner, J., Gahr, B.M., Huber, M., Boos, A., Rottbauer, W., Just, S. (2023) CRISPR/Cas9-mediated nexilin deficiency interferes with cardiac contractile function in zebrafish in vivo. Scientific Reports. 13:2267922679

Martin, K.E., Ravisankar, P., Beerens, M., MacRae, C.A., Waxman, J.S. (2023) Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish. eLIFE. 12:

Nagorska, A., Zaucker, A., Lambert, F., Inman, A., Toral-Perez, S., Gorodkin, J., Wan, Y., Smutny, M., Sampath, K. (2023) Translational control of furina by an RNA regulon is important for left-right patterning, heart morphogenesis and cardiac valve function. Development (Cambridge, England). 150(23):

Paolini, A., Sharipova, D., Lange, T., Abdelilah-Seyfried, S. (2023) Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling. Development (Cambridge, England). 150(18):

Halabi, R., Cechmanek, P.B., Hehr, C.L., McFarlane, S. (2022) Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development. Cell communication and signaling : CCS. 20:126

Huang, M., Akerberg, A.A., Zhang, X., Yoon, H., Joshi, S., Hallinan, C., Nguyen, C., Pu, W.T., Haigis, M.C., Burns, C.G., Burns, C.E. (2022) Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome. Nature communications. 13:5877

Perl, E., Ravisankar, P., Beerens, M.E., Mulahasanovic, L., Smallwood, K., Sasso, M.B., Wenzel, C., Ryan, T.D., Komár, M., Bove, K.E., MacRae, C.A., Weaver, K.N., Prada, C.E., Waxman, J.S. (2022) Stx4 is required to regulate cardiomyocyte Ca²⁺ handling during vertebrate cardiac development. HGG advances. 3:100115

Voisard, P., Diofano, F., Glazier, A.A., Rottbauer, W., Just, S. (2022) CRISPR/Cas9-Mediated Constitutive Loss of VCP (Valosin-Containing Protein) Impairs Proteostasis and Leads to Defective Striated Muscle Structure and Function In Vivo. International Journal of Molecular Sciences. 23(12)

Zink, M., Seewald, A., Rohrbach, M., Brodehl, A., Liedtke, D., Williams, T., Childs, S.J., Gerull, B. (2022) Altered Expression of TMEM43 Causes Abnormal Cardiac Structure and Function in Zebrafish. International Journal of Molecular Sciences. 23(17)

Bühler, A., Gahr, B.M., Park, D.D., Bertozzi, A., Boos, A., Dalvoy, M., Pott, A., Oswald, F., Kovall, R.A., Kühn, B., Weidinger, G., Rottbauer, W., Just, S. (2021) Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish. PLoS Genetics. 17:e1009890

Duong, T.B., Holowiecki, A., Waxman, J.S. (2021) Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm. Developmental Biology. 473:119-129

Park, D.D., Gahr, B.M., Krause, J., Rottbauer, W., Zeller, T., Just, S. (2021) Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish. International Journal of Molecular Sciences. 22(16):

Tessadori, F., Tsingos, E., Colizzi, E.S., Kruse, F., van den Brink, S.C., van den Boogaard, M., Christoffels, V.M., Merks, R.M., Bakkers, J. (2021) Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. eLIFE. 10:

Budine, T.E., de Sena-Tomás, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Kreze, L. (2020) Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development. Developmental Biology. 462(2):223-234

Holowiecki, A., Linstrum, K., Ravisankar, P., Chetal, K., Salomonis, N., Waxman, J.S. (2020) Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. Development (Cambridge, England). 147(5):

Lee, S.H., Hadipour-Lakmehsari, S., Murthy, H.R., Gibb, N., Miyake, T., Teng, A.C.T., Cosme, J., Yu, J.C., Moon, M., Lim, S., Wong, V., Liu, P., Billia, F., Fernandez-Gonzalez, R., Stagljar, I., Sharma, P., Kislinger, T., Scott, I.C., Gramolini, A.O. (2020) REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nature communications. 11:965

Li, S., Wen, H., Du, S. (2020) Defective sarcomere organization and reduced larval locomotion and fish survival in slow muscle heavy chain 1 (smyhc1) mutants. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34:1378-1397

Sam, J., Mercer, E.J., Torregroza, I., Banks, K.M., Evans, T. (2020) Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis. Biology Open. 9(6):

Santos-Ledo, A., Washer, S., Dhanaseelan, T., Eley, L., Alqatani, A., Chrystal, P.W., Papoutsi, T., Henderson, D.J., Chaudhry, B. (2020) Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression. PLoS Genetics. 16:e1008782

Bornhorst, D., Xia, P., Nakajima, H., Dingare, C., Herzog, W., Lecaudey, V., Mochizuki, N., Heisenberg, C.P., Yelon, D., Abdelilah-Seyfried, S. (2019) Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature communications. 10:4113

Burczyk, M.S., Burkhalter, M.D., Tena, T.C., Grisanti, L.A., Kauk, M., Matysik, S., Donow, C., Kustermann, M., Rothe, M., Cui, Y., Raad, F., Laue, S., Moretti, A., Zimmermann, W.H., Wess, J., Kühl, M., Hoffmann, C., Tilley, D.G., Philipp, M. (2019) Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI insight. 4(20):

Dohn, T.E., Ravisankar, P., Tirera, F.T., Martin, K.E., Gafranek, J.T., Duong, T.B., VanDyke, T.L., Touvron, M., Barske, L.A., Crump, J.G., Waxman, J.S. (2019) Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors. PLoS Genetics. 15:e1007962

Ghazizadeh, Z., Kiviniemi, T.O., Olafsson, S., Plotnick, D., Beerens, M., Zhang, K., Gillon, L., Steinbaugh, M., Barrera, V., Ho Sui, S., Werdich, A.A., Kapur, S., Eranti, A., Gunn, J., Jalkanen, J., Airaksinen, J., Kleber, A.G., Hollmén, M., MacRae, C.A. (2019) A Metastable Atrial State Underlies The Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation. Circulation. 141(4):301-312

Maerz, L.D., Burkhalter, M.D., Schilpp, C., Wittekindt, O.H., Frick, M., Philipp, M. (2019) Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish. Communications biology. 2:31

Seebacher, F., Simmonds, A.I.M. (2019) Histone deacetylase activity mediates thermal plasticity in zebrafish (Danio rerio). Scientific Reports. 9:8216

Song, Y.C., Dohn, T.E., Rydeen, A.B., Nechiporuk, A.V., Waxman, J.S. (2019) HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development. PLoS Genetics. 15:e1008165

Castillo-Robles, J., Ramírez, L., Spaink, H.P., Lomelí, H. (2018) smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish. Scientific Reports. 8:15369

Donat, S., Lourenço, M., Paolini, A., Otten, C., Renz, M., Abdelilah-Seyfried, S. (2018) Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis. eLIFE. 7:e28939

Huang, M., Jiao, J., Wang, J., Xia, Z., Zhang, Y. (2018) Characterization of acrylamide-induced oxidative stress and cardiovascular toxicity in zebrafish embryos. Journal of hazardous materials. 347:451-460

Mishra, S., Wu, S.Y., Fuller, A.W., Wang, Z., Rose, K.L., Schey, K.L., Mchaourab, H.S. (2018) Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart. The Journal of biological chemistry. 293(2):740-753

Paone, C., Rudeck, S., Etard, C., Strähle, U., Rottbauer, W., Just, S. (2018) Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response. Biochemical and Biophysical Research Communications. 496(2):339-345

Perna, A.F., Anishchenko, E., Vigorito, C., Zacchia, M., Trepiccione, F., D'Aniello, S., Ingrosso, D. (2018) Zebrafish, a Novel Model System to Study Uremic Toxins: The Case for the Sulfur Amino Acid Lanthionine. International Journal of Molecular Sciences. 19(5)

Pott, A., Bock, S., Berger, I.M., Frese, K., Dahme, T., Kessler, M., Rinné, S., Decher, N., Just, S., Rottbauer, W. (2018) Mutation of the Na⁺/K⁺-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish.. Journal of Molecular and Cellular Cardiology. 120:42-52

Segert, J., Schneider, I., Berger, I.M., Rottbauer, W., Just, S. (2018) Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish. Progress in Biophysics and Molecular Biology. 138:20-31

Abu-Taha, I.H., Heijman, J., Hippe, H.J., Wolf, N.M., El-Armouche, A., Nikolaev, V.O., Schäfer, M., Würtz, C., Neef, S., Voigt, N., Baczkó, I., Varró, A., Müller, M., Meder, B., Katus, H.A., Spiger, K., Vettel, C., Lehmann, L.H., Backs, J., Skolnik, E.Y., Lutz, S., Dobrev, D., Wieland, T. (2017) Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure. Circulation. 135(9):881-897

Akerberg, A.A., Henner, A., Stewart, S., Stankunas, K. (2017) Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation. Developmental Biology. 426(1):84-96

Colombo, S., de Sena-Tomás, C., George, V., Werdich, A.A., Kapur, S., MacRae, C.A., Targoff, K.L. (2017) nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression. Development (Cambridge, England). 145(3)

Duong, T.B., Ravisankar, P., Song, Y.C., Gafranek, J.T., Rydeen, A.B., Dohn, T.E., Barske, L.A., Crump, J.G., Waxman, J.S. (2017) Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Developmental Biology. 434(1):7-14

Ocaña, O.H., Coskun, H., Minguillón, C., Murawala, P., Tanaka, E.M., Galcerán, J., Muñoz-Chápuli, R., Nieto, M.A. (2017) A right-handed signalling pathway drives heart looping in vertebrates. Nature. 549:86-90

Pradhan, A., Zeng, X.I., Sidhwani, P., Marques, S.R., George, V., Targoff, K.L., Chi, N.C., Yelon, D. (2017) FGF signaling enforces cardiac chamber identity in the developing ventricle. Development (Cambridge, England). 144(7):1328-1338

Witzel, H.R., Cheedipudi, S., Gao, R., Stainier, D.Y., Dobreva, G.D. (2017) Isl2b regulates anterior second heart field development in zebrafish. Scientific Reports. 7:41043

Zhu, D., Fang, Y., Gao, K., Shen, J., Zhong, T.P., Li, F. (2017) Vegfa Impacts Early Myocardium Development in Zebrafish. International Journal of Molecular Sciences. 18(2)

Eden, M., Meder, B., Völkers, M., Poomvanicha, M., Domes, K., Branchereau, M., Marck, P., Will, R., Bernt, A., Rangrez, A., Busch, M., German Mouse Clinic Consortium, Hrabě de Angelis, M., Heymes, C., Rottbauer, W., Most, P., Hofmann, F., Frey, N. (2016) Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. Nature communications. 7:11317

Foglia, M.J., Cao, J., Tornini, V.A., Poss, K.D. (2016) Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium. Development (Cambridge, England). 143(10):1688-96

Just, S., Hirth, S., Berger, I.M., Fishman, M.C., Rottbauer, W. (2016) The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation. Biochemical and Biophysical Research Communications. 477(4):581-8

Just, S., Raphel, L., Berger, I.M., Bühler, A., Keßler, M., Rottbauer, W. (2016) Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS One. 11:e0167306

Roy, N.M., Ochs, J., Zambrzycka, E., Anderson, A. (2016) Glyphosate induces cardiovascular toxicity in Danio rerio. Environmental Toxicology and Pharmacology. 46:292-300

Rydeen, A.B., Waxman, J.S. (2016) Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. PLoS Biology. 14:e2000504

Wu, T.S., Yang, J.J., Wang, Y.W., Yu, F.Y., Liu, B.H. (2016) Mycotoxin ochratoxin A disrupts renal development via a miR-731/prolactin receptor axis in zebrafish.. Toxicology research. 5:519-529

Xie, H., Ye, D., Sepich, D., Lin, F. (2016) S1pr2/Gα13 signaling regulates the migration of endocardial precursors by controlling endoderm convergence. Developmental Biology. 414:228-43

Frese, K.S., Meder, B., Keller, A., Just, S., Haas, J., Vogel, B., Fischer, S., Backes, C., Matzas, M., Köhler, D., Benes, V., Katus, H.A., Rottbauer, W. (2015) RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish. Journal of Cell Science. 128(16):3030-40

George, V., Colombo, S., Targoff, K.L. (2015) An early requirement for nkx2.5 Ensures first and Second heart field ventricular identity and cardiac function into adulthood. Developmental Biology. 400(1):10-22

Zhao, X., Jiang, B., Hu, H., Mao, F., Mi, J., Li, Z., Liu, Q., Shao, C., Gong, Y. (2015) Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. Human molecular genetics. 24(3):853-64

Dietrich, A.C., Lombardo, V.A., Abdelilah-Seyfried, S. (2014) Blood Flow and Bmp Signaling Control Endocardial Chamber Morphogenesis. Developmental Cell. 30:367-377

Kalogirou, S., Malissovas, N., Moro, E., Argenton, F., Stainier, D.Y., Beis, D. (2014) Intracardiac Flow Dynamics Regulate Atrioventricular Valve Morphogenesis. Cardiovascular research. 104(1):49-60

Kelly, M.L., Astsaturov, A., Rhodes, J., Chernoff, J. (2014) A Pak1/Erk Signaling Module Acts through Gata6 to Regulate Cardiovascular Development in Zebrafish. Developmental Cell. 29:350-9

Peralta, M., González-Rosa, J.M., Marques, I.J., Mercader, N. (2014) The Epicardium in the Embryonic and Adult Zebrafish. Journal of developmental biology. 2:101-116

Rydeen, A.B., Waxman, J.S. (2014) Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm. Development (Cambridge, England). 141:1638-48

Schindler, Y.L., Garske, K.M., Wang, J., Firulli, B.A., Firulli, A.B., Poss, K.D., Yelon, D. (2014) Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. Development (Cambridge, England). 141(16):3112-22

Superina, S., Borovina, A., and Ciruna, B. (2014) Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry. Developmental Biology. 387(2):154-166

Zeng, X.X., Yelon, D. (2014) Cadm4 Restricts the Production of Cardiac Outflow Tract Progenitor Cells. Cell Reports. 7(4):951-60

Chen, Y.H., Pai, C.W., Huang, S.W., Chang, S.N., Lin, L.Y., Chiang, F.T., Lin, J.L., Hwang, J.J., and Tsai, C.T. (2013) Inactivation of Myosin binding protein C homolog in zebrafish as a model for human cardiac hypertrophy and diastolic dysfunction. Journal of the American Heart Association. 2(5):e000231

Haas, J., Frese, K.S., Park, Y.J., Keller, A., Vogel, B., Lindroth, A.M., Weichenhan, D., Franke, J., Fischer, S., Bauer, A., Marquart, S., Sedaghat-Hamedani, F., Kayvanpour, E., Kohler, D., Wolf, N.M., Hassel, S., Nietsch, R., Wieland, T., Ehlermann, P., Schultz, J.H., Dosch, A., Mereles, D., Hardt, S., Backs, J., Hoheisel, J.D., Plass, C., Katus, H.A., and Meder, B. (2013) Alterations in cardiac DNA methylation in human dilated cardiomyopathy. EMBO Molecular Medicine. 5(3):413-429

Li, H., Zhong, Y., Wang, Z., Gao, J., Xu, J., Chu, W., Zhang, J., Fang, S., and Du, S.J. (2013) Smyd1b is required for skeletal and cardiac muscle function in zebrafish. Molecular biology of the cell. 24(22):3511-21

Müller, I.I., Melville, D.B., Tanwar, V., Rybski, W.M., Mukherjee, A., Shoemaker, B.M., Wang, W.D., Schoenhard, J.A., Roden, D.M., Darbar, D., Knapik, E.W., and Hatzopoulos, A.K. (2013) Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Disease models & mechanisms. 6(2):332-341

Novikov, N., and Evans, T. (2013) Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling. Development (Cambridge, England). 140(18):3787-98

Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T. (2013) Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Developmental Biology. 381(2):389-400

Sorrell, M.R., Dohn, T.E., D'Aniello, E., and Waxman, J.S. (2013) Tcf7l1 proteins cell autonomously restrict cardiomyocyte and promote endothelial specification in zebrafish. Developmental Biology. 380(2):199-210

Targoff, K.L., Colombo, S., George, V., Schell, T., Kim, S.H., Solnica-Krezel, L., and Yelon, D. (2013) Nkx genes are essential for maintenance of ventricular identity. Development (Cambridge, England). 140(20):4203-4213

Veerkamp, J., Rudolph, F., Cseresnyes, Z., Priller, F., Otten, C., Renz, M., Schaefer, L., and Abdelilah-Seyfried, S. (2013) Unilateral dampening of bmp activity by nodal generates cardiac left-right asymmetry. Developmental Cell. 24(6):660-667

Wu, T.S., Yang, J.J., Yu, F.Y., and Liu, B.H. (2013) Cardiotoxicity of mycotoxin citrinin and involvement of microRNA-138 in zebrafish embryos. Toxicological sciences : an official journal of the Society of Toxicology. 136(2):402-12

Yan, L., Zhou, Y., Yu, S., Ji, G., Wang, L., Liu, W., and Gu, A. (2013) 8-Oxoguanine DNA glycosylase 1 (ogg1) maintains the function of cardiac progenitor cells during heart formation in zebrafish. Experimental cell research. 319(19):2954-63

Zhang, R., Han, P., Yang, H., Ouyang, K., Lee, D., Lin, Y.F., Ocorr, K., Kang, G., Chen, J., Stainier, D.Y., Yelon, D., and Chi, N.C. (2013) In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498(7455):497-501

de Pater, E., Ciampricotti, M., Priller, F., Veerkamp, J., Strate, I., Smith, K., Lagendijk, A.K., Schilling, T.F., Herzog, W., Abdelilah-Seyfried, S., Hammerschmidt, M., and Bakkers, J. (2012) Bmp Signaling Exerts Opposite Effects on Cardiac Differentiation. Circulation research. 110(4):578-587

Dohn, T.E., and Waxman, J.S. (2012) Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafish. Developmental Biology. 361(2):364-76

Dong, W., Yang, Z., Yang, F., Wang, J., Zhuang, Y., Xu, C., Zhang, B., Tian, X.L., and Liu, D. (2012) Suppression of rap1 impairs cardiac myofibrils and conduction system in zebrafish. PLoS One. 7(11):e50960

Ma, Y., Wu, M., Li, D., Li, X.Q., Li, P., Zhao, J., Luo, M.N., Guo, C.L., Lu, C.L., and Ma, X. (2012) Embryonic development toxicity of selenite in zebrafish (Danio rerio) and prevention with folic acid. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 508:2854-2863

Otten, C., van der Ven, P.F., Lewrenz, I., Paul, S., Steinhagen, A., Busch-Nentwich, E., Eichhorst, J., Wiesner, B., Stemple, D., Strähle, U., Fürst, D.O., and Abdelilah-Seyfried, S. (2012) Xirp proteins mark injured skeletal muscle in zebrafish. PLoS One. 7(2):e31041

Singleman, C., and Holtzman, N.G. (2012) Analysis of post-embryonic heart development and maturation in the zebrafish, Danio rerio. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(12):1993-2004

Völkers, M., Dolatabadi, N., Gude, N., Most, P., Sussman, M.A., and Hassel, D. (2012) Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish. Journal of Cell Science. 125(2):287-294

Hami, D., Grimes, A.C., Tsai, H.J., and Kirby, M.L. (2011) Zebrafish cardiac development requires a conserved secondary heart field. Development (Cambridge, England). 138(11):2389-2398

Just, S., Berger, I.M., Meder, B., Backs, J., Keller, A., Marquart, S., Frese, K., Patzel, E., Rauch, G.J., Tübingen 2000 Screen Consortium, Katus, H.A., and Rottbauer, W. (2011) Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity. Circulation. 124(3):324-34

Just, S., Meder, B., Berger, I.M., Etard, C., Trano, N., Patzel, E., Hassel, D., Marquart, S., Dahme, T., Vogel, B., Fishman, M.C., Katus, H.A., Strähle, U., and Rottbauer, W. (2011) The myosin-interacting protein SMYD1 is essential for sarcomere organization. Journal of Cell Science. 124(Pt 18):3127-36

Kawahara, G., Serafini, P.R., Myers, J.A., Alexander, M.S., and Kunkel, L.M. (2011) Characterization of zebrafish dysferlin by morpholino knockdown. Biochemical and Biophysical Research Communications. 413(2):358-63

Patra, C., Diehl, F., Ferrazzi, F., van Amerongen, M.J., Novoyatleva, T., Schaefer, L., Mühlfeld, C., Jungblut, B., and Engel, F.B. (2011) Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish. Development (Cambridge, England). 138(20):4499-4509

Scott, J.A., Incardona, J.P., Pelkki, K., Shepardson, S., and Hodson, P.V. (2011) AhR2-mediated, CYP1A-independent cardiovascular toxicity in zebrafish (Danio rerio) embryos exposed to retene. Aquatic toxicology (Amsterdam, Netherlands). 101(1):165-174

Sedletcaia, A., and Evans, T. (2011) Heart chamber size in zebrafish is regulated redundantly by duplicated tbx2 genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(6):1548-1557

Totong, R., Schell, T., Lescroart, F., Ryckebüsch, L., Lin, Y.F., Zygmunt, T., Herwig, L., Krudewig, A., Gershoony, D., Belting, H.G., Affolter, M., Torres-Vazquez, J., and Yelon, D. (2011) The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis. Development (Cambridge, England). 138(19):4199-4205

Wythe, J.D., Jurynec, M.J., Urness, L.D., Jones, C.A., Sabeh, M.K., Werdich, A.A., Sato, M., Yost, H.J., Grunwald, D.J., MacRae, C.A., and Li, D.Y. (2011) Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Disease models & mechanisms. 4(5):607-21

Zhou, Y., Cashman, T.J., Nevis, K.R., Obregon, P., Carney, S.A., Liu, Y., Gu, A., Mosimann, C., Sondalle, S., Peterson, R.E., Heideman, W., Burns, C.E., and Burns, C.G. (2011) Latent TGF-β binding protein 3 identifies a second heart field in zebrafish. Nature. 474(7353):645-8

Camarata, T., Krcmery, J., Snyder, D., Park, S., Topczewski, J., and Simon, H.G. (2010) Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation. Developmental Biology. 337(2):233-245

Clemen, C.S., Tangavelou, K., Strucksberg, K.H., Just, S., Gaertner, L., Regus-Leidig, H., Stumpf, M., Reimann, J., Coras, R., Morgan, R.O., Fernandez, M.P., Hofmann, A., Müller, S., Schoser, B., Hanisch, F.G., Rottbauer, W., Blümcke, I., von Hörsten, S., Eichinger, L., and Schröder, R. (2010) Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases. Brain : a journal of neurology. 133(10):2920-2941

Meder, B., Just, S., Vogel, B., Rudloff, J., Gärtner, L., Dahme, T., Huttner, I., Zankl, A., Katus, H.A., and Rottbauer, W. (2010) JunB-CBF{beta} signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure. Journal of Cell Science. 123(Pt 15):2613-2620

Murata, K., Nunomura, W., Takakuwa, Y., and Cherr, G.N. (2010) Two different unique cardiac isoforms of protein 4.1R in zebrafish, Danio rerio, and insights into their cardiac functions as related to their unique structures. Development, growth & differentiation. 52(7):591-602

Myhre, J.L., and Pilgrim, D.B. (2010) Cellular differentiation in primary cell cultures from single zebrafish embryos as a model for the study of myogenesis. Zebrafish. 7(3):255-266

Sogah, V.M., Serluca, F.C., Fishman, M.C., Yelon, D.L., MacRae, C.A., and Mably, J.D. (2010) Distinct troponin C isoform requirements in cardiac and skeletal muscle. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(11):3115-3123

Will, R.D., Eden, M., Just, S., Hansen, A., Eder, A., Frank, D., Kuhn, C., Seeger, T.S., Oehl, U., Wiemann, S., Korn, B., Koegl, M., Rottbauer, W., Eschenhagen, T., Katus, H.A., and Frey, N. (2010) Myomasp/LRRC39, a Heart- and Muscle-Specific Protein, Is a Novel Component of the Sarcomeric M-Band and Is Involved in Stretch Sensing. Circulation research. 107(10):1253-1264

Ghosh, T.K., Song, F.F., Packham, E.A., Buxton, S., Robinson, T.E., Ronksley, J., Self, T., Bonser, A.J., and Brook, J.D. (2009) Physical Interaction between TBX5 and MEF2C Is Required for Early Heart Development. Molecular and cellular biology. 29(8):2205-2218

Hassel, D., Dahme, T., Erdmann, J., Meder, B., Huge, A., Stoll, M., Just, S., Hess, A., Ehlermann, P., Weichenhan, D., Grimmler, M., Liptau, H., Hetzer, R., Regitz-Zagrosek, V., Fischer, C., Nürnberg, P., Schunkert, H., Katus, H.A., and Rottbauer, W. (2009) Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nature medicine. 15(11):1281-1288

Hippe, H.J., Wolf, N.M., Abu-Taha, I., Mehringer, R., Just, S., Lutz, S., Niroomand, F., Postel, E.H., Katus, H.A., Rottbauer, W., and Wieland, T. (2009) The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function. Proceedings of the National Academy of Sciences of the United States of America. 106(38):16269-16274

Ko, S.K., Jin, H.J., Jung, D.W., Tian, X., and Shin, I. (2009) Cardiosulfa, a Small Molecule that Induces Abnormal Heart Development in Zebrafish, and Its Biological Implications. Angewandte Chemie (International ed. in English). 48(42):7809-7812

Li, D., Lu, C., Wang, J., Hu, W., Cao, Z., Sun, D., Xia, H., and Ma, X. (2009) Developmental mechanisms of arsenite toxicity in zebrafish (Danio rerio) embryos. Aquatic toxicology (Amsterdam, Netherlands). 91(3):229-237

Marques, S.R., and Yelon, D. (2009) Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality. Developmental Biology. 328(2):472-482

Meder, B., Laufer, C., Hassel, D., Just, S., Marquart, S., Vogel, B., Hess, A., Fishman, M.C., Katus, H.A., and Rottbauer, W. (2009) A Single Serine in the Carboxyl Terminus of Cardiac Essential Myosin Light Chain-1 Controls Cardiomyocyte Contractility In Vivo. Circulation research. 104(5):650-659

Peal, D.S., Burns, C.G., MacRae, C.A., and Milan, D. (2009) Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(12):3103-3110

van't Padje, S., Chaudhry, B., Severijnen, L.A., van der Linde, H.C., Mientjes, E.J., Oostra, B.A., and Willemsen, R. (2009) Reduction in fragile X related 1 protein causes cardiomyopathy and muscular dystrophy in zebrafish. The Journal of experimental biology. 212(Pt 16):2564-2570

Bit-Avragim, N., Hellwig, N., Rudolph, F., Munson, C., Stainier, D.Y., and Abdelilah-Seyfried, S. (2008) Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko. Journal of Cell Science. 121(Pt 15):2503-2510

Hassel, D., Scholz, E.P., Trano, N., Friedrich, O., Just, S., Meder, B., Weiss, D.L., Zitron, E., Marquart, S., Vogel, B., Karle, C.A., Seemann, G., Fishman, M.C., Katus, H.A., and Rottbauer, W. (2008) Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. Circulation. 117(7):866-875

Lange, M., Kaynak, B., Forster, U.B., Tönjes, M., Fischer, J.J., Grimm, C., Schlesinger, J., Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S., and Sperling, S. (2008) Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes & Development. 22(17):2370-2384

Rohr, S., Otten, C., and Abdelilah-Seyfried, S. (2008) Asymmetric involution of the myocardial field drives heart tube formation in zebrafish. Circulation research. 102(2):e12-19

Targoff, K.L., Schell, T., and Yelon, D. (2008) Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number. Developmental Biology. 322(2):314-321

Thomas, N.A., Koudijs, M., van Eeden, F.J., Joyner, A.L., and Yelon, D. (2008) Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential. Development (Cambridge, England). 135(22):3789-3799

Waxman, J.S., Keegan, B.R., Roberts, R.W., Poss, K.D., and Yelon, D. (2008) Hoxb5b acts downstream of retinoic Acid signaling in the forelimb field to restrict heart field potential in zebrafish. Developmental Cell. 15(6):923-934

Incardona, J.P., Collier, T.K., and Scholz, N.L. (2004) Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons. Toxicology and applied pharmacology. 196(2):191-205

Joseph, E.M. (2004) Zebrafish IRX1b in the embryonic cardiac ventricle. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(4):720-726

Garrity, D.M., Childs, S., and Fishman, M.C. (2002) The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development (Cambridge, England). 129(19):4635-4645

Szeto, D.P., Griffin, K.J.P., and Kimelman, D. (2002) hrT is required for cardiovascular development in zebrafish. Development (Cambridge, England). 129(21):5903-5101

Peterson, R.T., Mably, J.D., Chen, J.-N., and Fishman, M.C. (2001) Convergence of distinct pathways to heart patterning reveals by the small molecule concentramide and the mutation heart-and-soul. Current biology : CB. 11:1481-1491

Walsh, E.C. and Stainier, D.Y. (2001) UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science (New York, N.Y.). 293(5535):1670-1673

Reifers, F., Walsh, E.C., Léger, S., Stainier, D.Y.R., and Brand, M. (2000) Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development (Cambridge, England). 127(2):225-235

Yelon, D., Ticho, B., Halpern, M.E., Ruvinsky, I., Ho, R.K., Silver, L.M., and Stainier, D.Y. (2000) The bHLH transcription factor Hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development (Cambridge, England). 127(12):2573-2582

Reiter, J.F., Alexander, J., Rodaway, A., Yelon, D., Patient, R., Holder, N., and Stainier, D.Y. (1999) Gata5 is required for the development of the heart and endoderm in zebrafish. Genes & Development. 13(22):2983-2995

Yelon, D., Horne, S.A., and Stainier, D.Y.R. (1999) Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. Developmental Biology. 214(1):23-37

Alexander, J., Stainier, D.Y.R., and Yelon, D. (1998) Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. Developmental genetics. 22:288-299

Chen, J.N., Haffter, P., Odenthal, J., Vogelsang, E., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., and Nüsslein-Volhard, C. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England). 123:293-302