Morpholino

MO3-phox2bb

ID
ZDB-MRPHLNO-130820-9
Name
MO3-phox2bb
Previous Names
  • P2BT2 splice donor (1)
Target
Sequence
5' - AAGTAAGCGGAGAATGTCCCACCTG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking MO.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 14
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-phox2bb
Expressed Gene Anatomy Figures
ascl1a Fig. 5 with image from Pei et al., 2013
dbh Fig. 2 with image,  Fig. 3 with image,  Fig. 6 with image from Pei et al., 2013
elavl3 Fig. 6 with image from Pei et al., 2013
phox2a Fig. 5 with image from Pei et al., 2013
phox2bb Fig. 5 with image,  Fig. 6 with image from Pei et al., 2013
th Fig. 2 with image,  Fig. 3 with image,  Fig. 5 with image,  Fig. 6 with image from Pei et al., 2013
Phenotype
Phenotype resulting from MO3-phox2bb
Phenotype Fish Figures
motor neuron axon morphology, abnormal nig2Tg + MO3-phox2bb Fig. 7 with image from Mitsuzawa et al., 2021
motor neuron axonal spine increased amount, abnormal nig2Tg + MO3-phox2bb Fig. 7 with image from Mitsuzawa et al., 2021
spinal cord axon decreased length, abnormal nig2Tg + MO3-phox2bb Fig. 7 with image from Mitsuzawa et al., 2021
spinal cord axon increased thickness, abnormal nig2Tg + MO3-phox2bb Fig. 7 with image from Mitsuzawa et al., 2021
swimming behavior disrupted, abnormal nig2Tg + MO3-phox2bb Fig. S4 from Mitsuzawa et al., 2021
sympathetic ganglion development disrupted, abnormal WT + MO3-phox2bb Fig. 2 with image,  Fig. 3 with image,  Fig. 6 with image from Pei et al., 2013
thigmotaxis disrupted, abnormal nig2Tg + MO3-phox2bb Fig. 7 with image from Mitsuzawa et al., 2021
Phenotype of all Fish created by or utilizing MO3-phox2bb
Phenotype Fish Conditions Figures
sympathetic ganglion development disrupted, abnormal WT + MO3-phox2bb standard conditions Fig. 2 with image,  Fig. 3 with image,  Fig. 6 with image from Pei et al., 2013
spinal cord axon increased thickness, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. 7 with image from Mitsuzawa et al., 2021
motor neuron axonal spine increased amount, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. 7 with image from Mitsuzawa et al., 2021
swimming behavior disrupted, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. S4 from Mitsuzawa et al., 2021
motor neuron axon morphology, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. 7 with image from Mitsuzawa et al., 2021
spinal cord axon decreased length, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. 7 with image from Mitsuzawa et al., 2021
thigmotaxis disrupted, abnormal nig2Tg + MO3-phox2bb standard conditions Fig. 7 with image from Mitsuzawa et al., 2021
sympathetic ganglion development disrupted, abnormal WT + MO3-ascl1a + MO3-phox2bb standard conditions Fig. 7 with image from Pei et al., 2013
Citations
TSV
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