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General Information
ZIRC
ZFIN ID: ZDB-GENE-050407-3
Gene Name: paired like homeobox 2Bb
Gene Symbol: phox2bb
Sequence Ontology ID : SO:0001217

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in enteric nervous  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 5 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH phox2bb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital central hypoventilation syndrome Central hypoventilation syndrome, congenital, with or without Hirschsprung disease 209880
Neuroblastoma with Hirschsprung disease 613013
{Neuroblastoma, susceptibility to, 2} 613013
DISEASE ASSOCIATED WITH phox2bb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sympathetic ganglion development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA phox2bb-202 (1) 2197
phox2bb-203 (1) 1004
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDS No data available
MARKER RELATIONSHIPS
phox2bb Contained in: [BAC] CH73-77D24 (1) (order this), DKEYP-50C7 (1)
phox2bb Encodes: [cDNA] MGC:194287 (1) (order this), MGC:194293 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001014818 (1) 2164 bp
Genomic GenBank:CT963086 (1) 84517 bp
Select Tool
Polypeptide UniProtKB:Q3T498 (1) 285 aa
Sequence Clusters UniGene:160837 (1)
Sequence Information (all 22)
ORTHOLOGY for phox2bb ( Chr: 14 )
CITATIONS (59)