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Fig. 1

Differentially expressed genes in xrcc1 crispants. (a) Genes that were significantly changed in both gRNA-t1/2 and gRNA-t5/6 crispants. Axes show − 1×log2 (fold change) in crispants compared to controls. Dot size indicates log10(mean false discovery rate). Lens proteins are highlighted in orange. (b) Normalized counts in controls (ctl) and crispants (mut) for selected genes that were differentially expressed in both experiments.

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