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Semenova et al., 2025 - Parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish

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Fig. 1

Differentially expressed genes in xrcc1 crispants. (a) Genes that were significantly changed in both gRNA-t1/2 and gRNA-t5/6 crispants. Axes show − 1×log₂ (fold change) in crispants compared to controls. Dot size indicates log₁₀(mean false discovery rate). Lens proteins are highlighted in orange. (b) Normalized counts in controls (ctl) and crispants (mut) for selected genes that were differentially expressed in both experiments.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.