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Liu et al., 2024 - Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development

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FIGURE 2

Comparing the expression pattern of the selected genes during craniofacial morphogenesis in mouse and zebrafish embryos. (A–D) Schematic illustrations of the craniofacial anatomy of the maxillary (A) and mandibular (B) regions of mice at E12.5 and zebrafish at 48 hours postfertilization (hpf) (C,D). (E–X) The expression pattern of Sox9 (sox9b), Zfhx4 (zfhx4), Zfhx3 (zfhx3b), Cjun (cjun), and Six1 (six1b) were examined using whole‐mount in situ hybridization. The samples are shown at the top, and the genes are shown on the left. (E′–X′) Schematic summary of the expression pattern of the selected genes. Black arrows, black arrowheads, and white arrowheads indicate Meckel's cartilages, ethmoid plate, and ceratohyal, respectively. Scale bars: 500 μm in V; 200 μm in X.

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