Gene
zfhx3b
- ID
- ZDB-GENE-030131-7577
- Name
- zinc finger homeobox 3b
- Symbol
- zfhx3b Nomenclature History
- Previous Names
-
- zfhx3
- fd23d06
- fj32b02
- im:7148790
- wu:fd23d06
- wu:fj32b02
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is expressed in nervous system and pharyngeal arch. Orthologous to human ZFHX3 (zinc finger homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154126 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial atrial fibrillation | Alliance | {Atrial fibrillation 8, susceptibility to} | 613055 |
| prostate cancer | Alliance | Prostate cancer, somatic | 176807 |
| spinocerebellar ataxia type 4 | Alliance | Spinocerebellar ataxia 4 | 600223 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR003604 | Matrin/U1-C-like, C2H2-type zinc finger |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR051968 | Zinc finger homeobox transcription regulators |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Matrin/U1-C-like, C2H2-type zinc finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger homeobox transcription regulators |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PQC4
|
2621 | |||||||
|
UniProtKB:A0A8M9QI68
|
3838 |
Interactions and Pathways
No data available
Plasmids
No data available