ZFIN Image: Li et al., 2024, Figure 6

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Figure 6

Slc1a4 deletion may inhibit Mauthner axons’ regeneration via Gap43 suppression. (a) RNA-seq analysis of P53 signaling pathway-related gene expression in mutant and wild-type lines. TPMs: Transcripts Per Kilobase of exon model per Million mapped reads. Assessed by unpaired t-test. * p < 0.05. ** p < 0.01. *** p < 0.001 (b) qPCR detection of tp53 and gap43 and rab13 expression. ** p < 0.01. (c,d) Gap43 was decreased in knockout group as shown via Western blot quantification. Data shown as mean ± sem. Unpaired Student’s two-tailed t-test; ** p < 0.01.

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Acknowledgments

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