ZFIN is now using GRCz12tu for Genomic Data
Gene
cdk1
- ID
- ZDB-GENE-010320-1
- Name
- cyclin dependent kinase 1
- Symbol
- cdk1 Nomenclature History
- Previous Names
-
- cdc2
- wu:fc30e01
- zgc:92032
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within neural retina development; regulation of mitotic cell cycle, embryonic; and spermatogenesis. Predicted to be located in centrosome. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Orthologous to human CDK1 (cyclin dependent kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclin-dependent kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T3L7 | InterPro | 302 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers