ZFIN ID: ZDB-GENE-990415-87
Gene Name: growth associated protein 43
Gene Symbol: gap43    Nomenclature History

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Previous Name: cb310 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have calmodulin binding activity and phospholipid binding activity. Involved in axon regeneration and tissue regeneration. Predicted to localize to cytoplasm; plasma membrane; and postsynaptic density. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human GAP43 (growth associated protein 43).
Genome Resources: Alliance (1),  Gene:30608 (1),  Ensembl(GRCz11):ENSDARG00000099744 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-gap43 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gap43 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gap43 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axon regeneration (more)
Cellular Component cell junction (more)
Molecular Function calmodulin binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-gap43 monoclonal IgG2a Mouse IHC Sigma-Aldrich
Santa Cruz Biotechnology, Inc.
4
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gap43
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(5xUAS:gap43-GFP) gap43GFP Danio rerio 1 15
tg(hsp70l:gap43-ma-ecfp) hsp70l ECFPgap43MA Danio rerio 1 1
MARKER RELATIONSHIPS
gap43 Encodes: [EST] cb310 (1) (order this)
[cDNA] MGC:91783 (1), MGC:192992 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131341 (1) 1151 nt
Genomic GenBank:CABZ01099793 (1) 7680 nt
Polypeptide UniProtKB:Q6DG93 (1) 194 aa
Sequence Information (all 19)
ORTHOLOGY for gap43 ( Chr: 15 )
CITATIONS (100)