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Chiba et al., 2017 - Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

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Fig. 1

Osteocrin (Ostn) is produced in cardiomyocytes of zebrafish. (A) Projection view of confocal images of the Tg(myl7:NLS-mCherry) heart at 72 hpf. A, atrium; V, ventricle. (B) RNA-seq analyses of mCherry-positive cardiomyocytes (CMs) from the hearts of Tg(myl7:NLS-mCherry) larvae at 72 hpf. Left and right y-axes report RPKM (reads per kilobase per million sequenced reads) values for the secretory molecules (left of the dashed line) and positive controls (right of the dashed line), respectively. Gray bars are used for structural proteins, white bars for secretory molecules. (C) Projection view of confocal images of the Tg(myl7:actn2-tdEos) heart at 72 hpf. (D) RNA-seq analyses of tdEos-positive CMs of Tg(myl7:actn2-tdEos). Axes descriptions as in B. Scale bars: 30 µm.

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