Gene

epoa

ID
ZDB-GENE-061218-3
Name
erythropoietin a
Symbol
epoa Nomenclature History
Previous Names
  • epo
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have erythropoietin receptor binding activity and hormone activity. Involved in nucleate erythrocyte development; pronephros development; and response to activity. Localizes to perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Is expressed in several structures, including brain; digestive system; eye; heart; and immune system. Orthologous to human EPO (erythropoietin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With epoa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial erythrocytosis 5 Alliance Erythrocytosis, familial, 5 617907
?Diamond-Blackfan anemia-like 617911
{Microvascular complications of diabetes 2} 612623
Associated With epoa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001323 Erythropoietin/thrombopoietin
Family IPR003013 Erythropoietin
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Erythropoietin Erythropoietin/thrombopoietin Four-helical cytokine-like, core
UniProtKB:Q2XNF5 183
UniProtKB:F1QKY2 182
UniProtKB:B1N8Y2 171
UniProtKB:B1N8Y1 186
UniProtKB:B3DI26 183
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations