Fig. 1
Fig. 1 The definitive hematopoiesis is defective in zebrafish mutantcas003 embryos.
(A, A′) The bright field images of zebrafish wild-type sibling (A) and mutantcas003 embryos (A′) showing no obvious difference at 5dpf. (B-G′) Whole-mount in situ hybridization (WISH) results of c-myb, ae1-globin, mpx, lyz and rag1 showing defective definitive hematopoiesis in mutantcas003 embryos (B′-G′) but not in sibling embryos (B-G) at 5dpf. The penetrance of the indicated phenotype is shown in the bottom left of each panel. (B-F, B′-F′) Lateral views; (G, G′) dorsal views. Black arrows indicate the position of caudal hematopoietic tissue (CHT); red arrows and circles show the position of thymus and kidney, respectively.