Gene
hbae1.1
- ID
- ZDB-GENE-980526-80
- Name
- hemoglobin, alpha embryonic 1.1
- Symbol
- hbae1.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Predicted to localize to hemoglobin complex. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and hemoglobin H disease. Is expressed in several structures, including hematopoietic cell; hematopoietic system; mesoderm; presumptive blood; and renal system. Orthologous to human HBA1 (hemoglobin subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 122 figures from 80 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
alpha thalassemia | Alliance | Thalassemias, alpha- | 604131 |
familial erythrocytosis 7 | Alliance | Erythrocytosis, familial, 7 | 617981 |
Heinz body anemia | Alliance | Heinz body anemias, alpha- | 140700 |
hemoglobin H disease | Alliance | Hemoglobin H disease, nondeletional | 613978 |
Methemoglobinemia, alpha type | 617973 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Globin | Globin-like superfamily | Globin/Protoglobin | Hemoglobin, alpha-type | Hemoglobin and related oxygen transporters | Hemoglobin, pi |
---|---|---|---|---|---|---|---|
UniProtKB:Q7ZT21
|
143 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA | hbae1-001 (1) | Havana | 877 nt | ||
mRNA |
hbae1.1-201
(1)
|
Ensembl | 633 nt | ||
mRNA | ottdart00000002407 (1) | Havana | 555 nt | ||
mRNA | ottdart00000002419 (1) | Havana | 838 nt |
Interactions and Pathways
No data available
Plasmids
No data available