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Fig. 7
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Fig. 7 Coinjection of MKK4-MO or JNK-MO Could Cancel the Dorsalizing Effect of aida-MO (A) Expression patterns of marker genes in wild-type embryos or embryos injected with 10 ng of aida-MO, 10 ng of MKK4-MO, 10 ng JNK-MO, or the aforementioned in combination. (B) Statistical data for (A). Injection of 300 pg of aida mRNA induced ventralization, while injection of 10 ng of aida-MO had the opposite effect. The dorsalized phenotype could be rescued by coinjection of aida mRNA.
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Reprinted from Developmental Cell, 13(2), Rui, Y., Xu, Z., Xiong, B., Cao, Y., Lin, S., Zhang, M., Chan, S.C., Luo, W., Han, Y., Lu, Z., Ye, Z., Zhou, H.M., Han, J., Meng, A., and Lin, S.C., A beta-Catenin-Independent Dorsalization Pathway Activated by Axin/JNK Signaling and Antagonized by Aida, 268-282, Copyright (2007) with permission from Elsevier. Full text @ Dev. Cell