Gene
rrm2
- ID
- ZDB-GENE-990415-25
- Name
- ribonucleotide reductase M2 polypeptide
- Symbol
- rrm2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including nervous system; pectoral fin musculature; pharyngeal arch 3-7 skeleton; proliferative region; and tail bud. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb111 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR030475 | Ribonucleotide reductase small subunit, acitve site |
| Family | IPR000358 | Ribonucleotide reductase small subunit family |
| Family | IPR033909 | Ribonucleotide reductase small subunit |
| Homologous_superfamily | IPR009078 | Ferritin-like superfamily |
| Homologous_superfamily | IPR012348 | Ribonucleotide reductase-like |
Domain Details Per Protein
| Protein | Length | Ferritin-like superfamily | Ribonucleotide reductase-like | Ribonucleotide reductase small subunit | Ribonucleotide reductase small subunit, acitve site | Ribonucleotide reductase small subunit family |
|---|---|---|---|---|---|---|
|
UniProtKB:P79733
|
386 | |||||
|
UniProtKB:G3G7U0
|
386 |
Interactions and Pathways
No data available
Plasmids
No data available