Gene

rrm2

ID
ZDB-GENE-990415-25
Name
ribonucleotide reductase M2 polypeptide
Symbol
rrm2 Nomenclature History
Previous Names
  • r2
  • cb111 (1)
  • chunp6884
  • etID309896.20 (1)
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Predicted to have ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including nervous system; pectoral fin musculature; pharyngeal arch 3-7 skeleton; proliferative region; and tail bud. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rrm2 Human Ortholog
No data available
Associated With rrm2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR030475 Ribonucleotide reductase small subunit, acitve site
Family IPR000358 Ribonucleotide reductase small subunit family
Family IPR033909 Ribonucleotide reductase small subunit
Homologous_superfamily IPR009078 Ferritin-like superfamily
Homologous_superfamily IPR012348 Ribonucleotide reductase-like
Domain Details Per Protein
Protein Length Ferritin-like superfamily Ribonucleotide reductase-like Ribonucleotide reductase small subunit Ribonucleotide reductase small subunit, acitve site Ribonucleotide reductase small subunit family
UniProtKB:A0A0R4ILJ6 189
UniProtKB:G3G7U0 386
UniProtKB:U3JAP5 227
UniProtKB:U3JAR5 225
UniProtKB:U3JB06 107
UniProtKB:U3JB36 180
UniProtKB:P79733 386
UniProtKB:A0A0R4ID34 157
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations