Gene

elavl1a

ID

ZDB-GENE-990415-245

Name

ELAV like RNA binding protein 1a

Symbol

elavl1a Nomenclature History

Previous Names

elavl1
elra (1)
elav-related A
etID309757.2 (1)
fa25f08
fb59a02
fc60g02
hua
wu:fa25f08
wu:fb59a02 (1)
wu:fc60g02 (1)
zHuA (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable RNA binding activity. Acts upstream of or within erythrocyte differentiation and positive regulation of angiogenesis. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Is expressed in oocyte. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55502 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elavl1a Human Ortholog

No data available

Associated With elavl1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034996	HuR, RNA recognition motif 2
Family	IPR002343	Paraneoplastic encephalomyelitis antigen
Family	IPR006548	Splicing factor ELAV/Hu
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	HuR, RNA recognition motif 2	Nucleotide-binding alpha-beta plait domain superfamily	Paraneoplastic encephalomyelitis antigen	RNA-binding domain superfamily	RNA recognition motif domain	Splicing factor ELAV/Hu
UniProtKB:A0A8M2BIL8 InterPro	340
UniProtKB:A0A8M3AQB0 InterPro	210
UniProtKB:Q9PTK5 InterPro	324

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	elavl1a-201 (1) Ensembl	Ensembl	2,193 nt	Select Tool ZFIN BLAST
mRNA	elavl1a-202 (1) Ensembl	Ensembl	3,337 nt	Select Tool ZFIN BLAST
mRNA	elavl1a-203 (1) Ensembl	Ensembl	581 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-elavl1	monoclonal	elavl1a	IgG1 , k	Mouse	IHC	Life Technologies (Invitrogen)	7
Ab2-elavl1	polyclonal	elavl1a			WB		1

Plasmids

Addgene:175315

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations