Gene

hoxd13a

ID
ZDB-GENE-990415-119
Name
homeobox D13a
Symbol
hoxd13a Nomenclature History
Previous Names
  • hoxd-13
  • hoxd13
  • zgc:110511
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within multicellular organism development and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including cloaca; mesenchyme; pectoral fin bud; periderm; and tail bud. Human ortholog(s) of this gene implicated in brachydactyly-syndactyly syndrome; clubfoot; cryptorchidism; and dysostosis (multiple). Orthologous to human HOXD13 (homeobox D13).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxd13a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
brachydactyly type D Alliance Brachydactyly, type D 113200
brachydactyly type E1 Alliance Brachydactyly, type E 113300
brachydactyly-syndactyly syndrome Alliance ?Brachydactyly-syndactyly syndrome 610713
syndactyly type 5 Alliance Syndactyly, type V 186300
synpolydactyly Alliance Synpolydactyly 1 186000
Associated With hoxd13a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily
UniProtKB:A8E5N0 256
UniProtKB:Q90472 256
UniProtKB:B0S5Z0 256
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations