header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-216
Gene Name: engrailed homeobox 1a
Gene Symbol: en1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: en-1, en1, eng1 (1), eng1a, zgc:100771

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in axonogenesis involved in innervation. Predicted to localize to the RSC-type complex. Human ortholog(s) of this gene implicated in Parkinson's disease. Is expressed in several structures, including adaxial cell; midbrain hindbrain boundary neural rod; musculature system; pectoral fin bud; and somite. Orthologous to human EN1 (engrailed homeobox 1).
Genome Resources: Alliance (1),  Gene:30244 (1),  Ensembl(GRCz11):ENSDARG00000014321 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-en1a N/A 1
MO2-en1a N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH en1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH en1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axonogenesis involved in innervation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-eng monoclonal IgG1 , k Mouse IHC Developmental Studies Hybridoma Bank
108
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM en1a No data available
MARKER RELATIONSHIPS
en1a Encodes: [EST] IMAGE:7138684 (1) (order this)
[cDNA] MGC:100771 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131045 (1)
Polypeptide UniProtKB:Q04896 (1) 231 aa
Sequence Clusters UniGene:75072 (1)
Sequence Information (all 14)
ORTHOLOGY for en1a ( Chr: 9 )
CITATIONS (65)