Gene
sfpq
- ID
- ZDB-GENE-040426-2452
- Name
- splicing factor proline/glutamine-rich
- Symbol
- sfpq Nomenclature History
- Previous Names
-
- hm:zeh0027
- wis (1)
- wu:fa11h12
- wu:fd10f03
- zgc:85935
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Acts upstream of or within central nervous system development and negative regulation of axon regeneration. Located in neuron projection and nucleus. Is expressed in brain; eye; gut; heart; and muscle cell. Orthologous to human SFPQ (splicing factor proline and glutamine rich).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85935 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 26 figures from 12 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR012975 | NOPS |
| Domain | IPR034525 | PSF, RNA recognition motif 1 |
| Domain | IPR034526 | PSF, NOPS domain |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | NOPS | Nucleotide-binding alpha-beta plait domain superfamily | PSF, NOPS domain | PSF, RNA recognition motif 1 | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NUU2 | InterPro | 619 | ||||||
| UniProtKB:A0A8M1PEX4 | InterPro | 638 |
Interactions and Pathways
No data available
Plasmids
No data available