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Fig. S8

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ZDB-FIG-260618-14

Publication

Biswas et al., 2026 - Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum

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Fig. S8

Heterozygous δ2-pcdh mutants exhibit altered neural dynamics.
A-C. Latent dynamics computed from trial averaged neural data collected in heterozygous (A) pcdh19^Δprom, (B) pcdh19^-10bp and (C) pcdh17^-5bp mutant larvae. Individual traces are shown on top of the group variance, shaded in blue. The value, r̄, represents the mean correlation of each individual neural mode to the wild type average of that neural mode. D. The correlation of individual trial-averaged neural modes to the wild type average (wild type, n = 9; pcdh19^Δprom, n = 20; pcdh19^-10bp, n = 14; pcdh17^-5bp, n = 11). (*p < 0.05, Dunnett’s test). E. Pairwise within-group correlations of neural modes for wild type (purple) and pcdh17 mutants (orange). (wild type, n = 36; pcdh19^Δprom, n = 190; pcdh19^-10bp, n = 91; pcdh17^-5bp, n = 55; **p < 0.0001, *p,0.05, Dunnett’s test).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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