FIGURE

Fig 4

ID

ZDB-FIG-260606-16

Publication

Biswas et al., 2026 - Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum

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Fig 4

Mutations in pcdh17 lead to altered neural dynamics.
A. Latent dynamics computed from trial averaged neural data collected in homozygous pcdh17^-5bp mutant larvae. Individual traces are in orange and the shaded area in blue indicates the group variance. The value, r̄, represents the mean correlation of each individual neural mode to the group average of that neural mode. We obtained a total of 3561 visually-responsive neurons. B. The correlation of individual trial-averaged neural modes to the wild type average (wild type, n = 9; pcdh17^-5bp, n = 13). C. Pairwise within-group correlations of neural modes for wild type (purple) and pcdh17 mutants (orange). (wild type, n = 36; pcdh17^-5bp, n = 78; *p,0.05, Dunnett’s test). D. Neural modes were averaged for pcdh17^-5bp mutants (orange) and the average was compared to the wild type average (purple). The value, r̄, represents the correlation of each mutant average with the wild type average.

Expression Data

Gene:	GCaMP
Fish:	pcdh17^os69/os69; os78Tg/os78Tg
Condition:	lighting conditions
Anatomical Term:	optic tectum
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pcdh17^os69/os69; os78Tg/os78Tg
Condition:	lighting conditions
Observed In:	optic tectum optic tectum visual perception
Stage:	Day 6

Phenotype Detail

Acknowledgments

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