FIGURE

Figure 5.

ID

ZDB-FIG-260423-53

Publication

Wei et al., 2026 - A Novel CRYBB2 Splicing Mutation Is Associated With Lens Extracellular Matrix Remodeling and Vascular Alterations in Congenital Cataract

Other Figures

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Figure 5.

Single-cell atlas and intercellular communication changes upon crybb2 knockout. (A) UMAP visualization of broad cell type annotations from single-cell transcriptomic data. (B) Cell-cell communication networks inferred by CellChat, comparing control and crybb2 knockout groups, shown by interaction number (top) and interaction strength (bottom). (C) UMAP visualization of sub-cluster annotations within selected vascular- and lens-related populations. (D) Dot plot summarizing significantly enriched ligand-receptor interactions between sub-clusters in control and crybb2 knockout conditions.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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