FIGURE

Fig. 7

ID

ZDB-FIG-260408-7

Publication

Hernandez Herrera et al., 2026 - ercc6 deficient zebrafish exhibit UV and metronidazole sensitivity, increased oxygen consumption, and impaired hair cell mechanoelectrical transduction which can be restored by the superoxide dismutase mimetic MnTBAP

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Fig. 7

Hair cell counts after UVC exposure. (A) Graph showing number of cells per neuromast, per larvae at 1-, 24-, and 48-h post exposure (HPE; 5- to 7-days post fertilization). (B) Representative confocal images after AlexaFluor phalloidin 488 staining of the MI1 neuromast of 5- to 7-days post fertilization zebrafish larvae. Cell counts were comparable between both genotypes and all exposure groups after 30 s UVC exposure. Data is from 10 replicate experiments with at least 3 embryos per group, per experiment and is represented by mean ± SD. Each data point represents a single zebrafish larva. Differences between groups were analyzed via two-way ANOVA with multiple comparisons (no differences found) scale bar: 5 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ercc6^{mn3001/mn3001}
Condition:	ultraviolet light
Observed In:	neuromast hair cell
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.