FIGURE

Fig. 6.

ID

ZDB-FIG-260401-46

Publication

Karchner et al., 2026 - Using fish models to understand the role of aryl hydrocarbon receptor (AHR)-interacting protein (AIP) in controlling sensitivity and resistance to dioxin-like compounds in vivo

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Fig. 6.

Wild-type (WT) and mutant (MUT) AIP transcripts in WT, HET, and HMZ mutant aip^wh239 larvae at 3 dpf (A, experiment 3a) and aip^wh86 larvae at 5 dpf (B, experiment 3b). Transcript numbers were assessed using RNA-seq data. Data represent the number of reads that overlap the deletion site in the aip gene, averaged over 4 replicate samples. The numbers include both maternal and zygotic transcripts. Results show that HMZ mutant embryos have some WT maternal transcripts at 3 and 5 dpf. Mutant transcripts appear to be rapidly degraded, suggesting nonsense-mediated decay. Abbreviations used: WT: Wild-type; HET: Heterozygous; HMZ: Homozygous.

Expression Data

Gene:	aip
Fish:	TL aip^wh239/wh239 (TL) aip^wh239/+ (TL)
Anatomical Term:	whole organism
Stage Range:	Protruding-mouth to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	aip^wh239/wh239 (TL) aip^wh239/+ (TL)
Observed In:	whole organism
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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