FIGURE

Figure 7.

ID

ZDB-FIG-260105-109

Publication

Michno et al., 2025 - Pneumolysin-dependent and independent non-canonical autophagy processes mediate host defense against pneumococcal infection

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Figure 7.

Both LAP and STIL are evoked in response to S. pneumoniae. (A) Representative confocal images of control, cyba, tecpr1a and cyba tecpr1a double knockdown CMV:GFP-Lc3 larvae infected systemically with approximately 1600 CFU of mKate2-labeled D39 δcps S. pneumoniae fixed at 2 hpi. (B) Quantification of Lc3 associations with intracellular S. pneumoniae within infected phagocytes of fixed cyba, tecpr1a and cyba tecpr1a double knockdown CMV:GFP-Lc3 larvae. Data are shown as mean ± standard deviation (SD). Data obtained from two independent experiments. (C) Numbers of viable colony forming units (CFUs) over time of control, cyba, tecpr1a and cyba tecpr1a double knockdown larvae. Data obtained from two independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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