FIGURE

Figure 7

ID

ZDB-FIG-251004-91

Publication

Stemerdink et al., 2025 - Exploring exon excision as a therapeutic intervention strategy for the future treatment of ADGRV1-associated retinitis pigmentosa

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Figure 7

ERG recordings reveal normal retinal function in adgrv1^Δexon40-42 zebrafish

(A) Representative ERG traces of wild-type, adgrv1^rmc22, and adgrv1^Δexon40-42 zebrafish larvae (7 dpf). (B) Maximum B-wave amplitudes following a light stimulus of 1,000 lux. The mean maximum B-wave amplitude of adgrv1^Δexon40-42 larvae is similar to those observed in wild types, whereas adgrv1^rmc22 larvae show a significant decrease in maximum B-wave amplitudes (∗∗∗p = 0.0001; ∗∗∗∗p < 0.0001; one-way ANOVA followed by Tukey’s multiple comparison test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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