FIGURE

Fig. 8

ID

ZDB-FIG-250916-29

Publication

Stefan et al., 2025 - Polypharmacology translates between species and phylogenetic distance: A functional, bioinformatic, and structural study on organic anion transporting polypeptides

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Fig. 8

Phylogenetic tree of OATPs of typical mammals, clinically relevant species, and members from four clades of bony and cartilaginous fish based on protein sequences retrieved from UniProt (https://www.uniprot.org). Abbreviations (alphabetically sorted): ar – Acipenser ruthenus (starlet); bt – Bos taurus (cattle); cl – Canis lupus (wolf); cm – Callorhinchus milii (Australian ghostshark); dm – Drosophila melanogaster (fruitfly); dr – Danio rerio (zebrafish); ec – Equus caballus (horse); fc – Felis catus (cat); hs − Homo sapiens (human); lc – Latimeria chalumnae (west Indian ocean coelacanth); mam – Macaca mulatta (rhesus macaque); mum – Mus musculus (house mouse); pt – Pan troglodytes (chimpanzee); rn – Rattus norvegicus (brown rat); ss – Sus scrofa (wild boar).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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