FIGURE

Fig. 5

ID

ZDB-FIG-250909-36

Publication

Guzman et al., 2025 - B-rich colistin and B-pure colistin as novel strategies to increase the therapeutic window of polymyxin antibiotic therapy

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Lethality assessment of two types of colistin (A-rich and B-rich) co-exposed to melatonin, EGCG, and curcumin. Zebrafish embryos at 6 hpf were co-exposed to the MTC of melatonin, EGCG, or curcumin together with A) A-rich colistin or B) B-rich colistin until 72 hpf. Lethality data are presented as the mean accumulated lethality ± SEM from three independent experiments, each using 10 embryos per group (total of 30 embryos/group). C) Curcumin fluorescence was quantified in six embryos per group after an exposure to 5 or 10 µM of curcumin in combination with 5 or 10 µM of B-rich colistin. D) Representative images of curcumin fluorescence in zebrafish embryos at 24 hpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomed. Pharmacother.